寒战和发热的周期能治愈双相情感障碍的躁狂发作吗？
Can cycles of chills and fever resolve bipolar disorder mania?
作者信息
Setsaas Audun, Vaaler Arne Einar
机构信息
Division of Psychiatry, Department of Nidaros DPS, St Olavs University Hospital, Trondheim, Norway.
出版信息
BMJ Case Rep. 2014 Apr 11;2014:bcr2013203127. doi: 10.1136/bcr-2013-203127.
Abstract
Treatment resistance is common in populations of patients with bipolar disorder stressing the need for new therapeutic strategies. Favourable effects of fever on mental disease have been noted throughout history. Today there is increasing evidence that immunological processes are involved in the pathophysiology of mental disorders. We present a case in which a patient with treatment resistant bipolar disorder mania seemingly recovered as a result of recurrent fever. This indicates that artificial fever might become a last resort therapy for treatment resistant mania.
摘要
治疗抵抗在双相情感障碍患者群体中很常见，这凸显了对新治疗策略的需求。纵观历史，发热对精神疾病的有利影响已被注意到。如今，越来越多的证据表明免疫过程参与了精神障碍的病理生理学。我们报告一例治疗抵抗性双相情感障碍躁狂症患者，其似乎因反复发热而康复。这表明人工发热可能成为治疗抵抗性躁狂症的一种终极疗法。
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