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亚历克西斯·卡雷尔(1873 - 1944):有远见的血管外科医生及器官移植先驱。

Alexis Carrel (1873-1944): visionary vascular surgeon and pioneer in organ transplantation.

作者信息

Aida Lai

机构信息

Department of Trauma and Orthopaedics Surgery, Frenchay Hospital, Bristol, UK

出版信息

J Med Biogr. 2014 Aug;22(3):172-5. doi: 10.1177/0967772013516899. Epub 2014 Apr 15.

Abstract

Alexis Carrel was a French surgeon in the 20th century. He made significant contributions to many advances in the fields of vascular surgery, cardiothoracic surgery and organ transplantation. He demonstrated that blood vessels can be united end-to-end and pioneered the triangulation suturing technique in vascular anastomosis. The methods he developed are still in use to this day. He insisted on the importance of absolute asepsis in vascular surgery when such practices were almost unheard of. He was also considered the father of solid organ transplantation. He was awarded the Nobel Prize in recognition of his work. Together with Charles Lindbergh, he developed the extracorporeal perfusion pump to keep organs alive outside the human body. His contribution to medicine also extended to tissue culture and wound management. He was one of the most controversial figures of his generation, believing in the idea of genetic superiority and eugenics and he was associated with fascism in the 1930s.

摘要

亚历克西·卡雷尔是20世纪的一位法国外科医生。他在血管外科、心胸外科和器官移植领域的诸多进展中做出了重大贡献。他证明了血管可以端端吻合,并开创了血管吻合术中的三角缝合技术。他所研发的方法至今仍在使用。在几乎无人知晓这种做法的时候,他就坚持绝对无菌在血管外科中的重要性。他还被视为实体器官移植之父。他因自己的工作而被授予诺贝尔奖。他与查尔斯·林德伯格共同研发了体外灌注泵,以使器官在人体外保持存活。他对医学的贡献还扩展到了组织培养和伤口处理。他是他那个时代最具争议的人物之一,信奉基因优越性和优生学的理念,并且在20世纪30年代与法西斯主义有所关联。

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