Nordberg Per, Hollenberg Jacob, Rosenqvist Mårten, Herlitz Johan, Jonsson Martin, Järnbert-Petterson Hans, Forsberg Sune, Dahlqvist Tobias, Ringh Mattias, Svensson Leif
Department of Clinical Science and Education Karolinska Institutet, Section of Cardiology, Södersjukhuset Stockholm, Sweden
Department of Clinical Science and Education Karolinska Institutet, Section of Cardiology, Södersjukhuset Stockholm, Sweden.
Eur Heart J Acute Cardiovasc Care. 2014 Dec;3(4):293-303. doi: 10.1177/2048872614532415. Epub 2014 Apr 16.
To determine the impact of a dual dispatch system, using fire fighters as first responders, in out-of-hospital cardiac arrest (OHCA) on short (30 days) and long term (three years) survival, and, to investigate the potential differences regarding in-hospital factors and interventions between the patient groups, such as the use of therapeutic hypothermia and cardiac catheterization.
OHCAs from 2004 (historical controls) and 2006-2009 (intervention period) were included. During the intervention period, fire fighters equipped with automated external defibrillators (AEDs) were dispatched in suspected OHCA. Logistic regression analyses of outcome data included: the intervention with dual dispatch, sex, age, location, aetiology, witnessed status, bystander-cardiopulmonary resuscitation, first rhythm and therapeutic hypothermia. In total, 2581 OHCAs were included (historical controls n=620, intervention period n=1961). Fire fighters initiated cardiopulmonary resuscitation and connected an AED before emergency medical services' arrival in 41% of the cases. The median time from dispatch to arrival of first responder or emergency medical services shortened from 7.7 in the control period to 6.7 min in the intervention period (p<0.001). The 30-day survival improved from 3.9% to 7.6% (p=0.001), adjusted odds ratio 2.8 (confidence interval 1.6-4.9). Survival to three years increased from 2.4% to 6.5% (p<0.001), adjusted odds ratio 3.8 (confidence interval 1.9-7.6). In the logistic regression analysis including in-hospital factors we found no outcome benefit of therapeutic hypothermia.
The implementation of a dual dispatch system using fire fighters in OHCA was associated with increased 30-day and three-year survival. No major differences in the in-hospital treatment were seen between the studied patient groups.
确定以消防员作为第一反应者的双重调度系统对院外心脏骤停(OHCA)患者短期(30天)和长期(三年)生存的影响,并调查患者组之间在院内因素和干预措施方面的潜在差异,如治疗性低温和心脏导管插入术的使用情况。
纳入2004年(历史对照)和2006 - 2009年(干预期)的院外心脏骤停病例。在干预期,配备自动体外除颤器(AED)的消防员被派往疑似院外心脏骤停现场。对结局数据进行逻辑回归分析,包括:双重调度干预、性别、年龄、地点、病因、是否有目击者、旁观者心肺复苏情况、初始心律和治疗性低温。总共纳入2581例院外心脏骤停病例(历史对照620例,干预期1961例)。在41%的病例中,消防员在紧急医疗服务到达之前就开始了心肺复苏并连接了自动体外除颤器。从调度到第一反应者或紧急医疗服务到达的中位时间从对照期的7.7分钟缩短至干预期的6.7分钟(p<0.001)。30天生存率从3.9%提高到7.6%(p = 0.001),调整后的优势比为2.8(置信区间1.6 - 4.9)。三年生存率从2.4%提高到6.5%(p<0.001),调整后的优势比为3.8(置信区间1.9 - 7.6)。在纳入院内因素的逻辑回归分析中,我们未发现治疗性低温对结局有获益。
在院外心脏骤停中实施以消防员为第一反应者的双重调度系统与30天和三年生存率的提高相关。在研究的患者组之间,未观察到院内治疗有重大差异。