Smith Jason A, Cuccurullo Sara J, Protzman Nicole M, Kooch Jason E
From the JFK Johnson Rehabilitation Institute, Edison, New Jersey (JAS, SJC); and Physical Medicine & Rehabilitation (JAS, JEK) and Clinical Education & Research Department (NMP), Coordinated Health, Bethlehem, Pennsylvania (JAS, NMP, JEK).
Am J Phys Med Rehabil. 2014 Aug;93(8):714-8. doi: 10.1097/PHM.0000000000000099.
Although Chiari malformations are much more prevalent than once believed, no study has described treatment with an interventional spinal procedure. The purpose of this report was to discuss the clinical course of a patient who was diagnosed with a Chiari malformation and treated with three cervical epidural injections. In 2012, a 50-yr-old woman presented to a neurology clinic with chronic suboccipital headaches, diplopia, and increasing numbness/tingling in her upper extremities. Magnetic resonance imaging confirmed a type I Chiari malformation and a cervical syrinx. The patient was treated with three cervical epidural injections, after which her symptoms exacerbated. Consequently, a posterior fossa suboccipital craniectomy with C1 laminectomy and excision of extradural and intradural adhesions was performed. After surgical intervention, notable neurologic improvements were observed. Given the marked worsening of symptoms, the present report suggests that interventional spinal procedures may be a contraindication in the presence of a Chiari malformation with a syrinx.
尽管Chiari畸形比以往认为的更为普遍,但尚无研究描述过采用介入性脊柱手术进行治疗的情况。本报告的目的是讨论一名被诊断为Chiari畸形并接受了三次颈椎硬膜外注射治疗的患者的临床病程。2012年,一名50岁女性因慢性枕下头痛、复视以及上肢麻木/刺痛加重前往神经科诊所就诊。磁共振成像证实为I型Chiari畸形和颈椎空洞症。该患者接受了三次颈椎硬膜外注射治疗,之后症状加重。因此,实施了后颅窝枕下颅骨切除术、C1椎板切除术以及硬膜外和硬膜内粘连切除术。手术干预后,观察到显著的神经功能改善。鉴于症状明显恶化,本报告提示,对于存在伴有空洞症的Chiari畸形患者,介入性脊柱手术可能是禁忌。