Ouss Alexandre J, Riezebos Robert K
Department of Cardiology, Onze Lieve Vrouwe Gasthuis Hospital, Amsterdam, the Netherlands.
J Cardiovasc Ultrasound. 2014 Mar;22(1):23-7. doi: 10.4250/jcu.2014.22.1.23. Epub 2014 Mar 31.
A distinct velocity pattern represented by a "notch" is observed during the time interval between the end of the systolic and the onset of the early diastolic velocity wave on longitudinal myocardial velocity curve. The origin of the post-systolic velocity notch (PSN) has not been resolved.
The high frame rate color tissue Doppler imaging of the apical longitudinal axis was performed in 32 healthy subjects.
The time delays of the PSN onset at the posterior aortic wall (AW), the mid anteroseptal wall (MAS) and the posterior mitral annulus (MA) relatively to the anterior aortic annulus (AA) were found to be significantly longer than zero (5.1 ± 2.2, 6.0 ± 2.3, 6.8 ± 2.8 ms; p < 0.001). The amplitude was the highest at the AA when compared to the AW, the MAS and the MA (4.77 ± 1.28 vs. 2.88 ± 1.11, 2.15 ± 0.73, 2.44 ± 1.17 cm/s; p < 0.001). A second PSN spike was identifiable in 10/32 (31%) of the studied subjects at the AA. Of these, 9 (28%) exhibited a second PSN spike at the AW, 3 (9%) at the MAS and no one at the MA.
The AA represents the site of the earliest onset and maximal amplitude of the PSN on the longitudinal velocity curve suggesting its mechanism to be that of an energy release at the instant of the aortic valve closure causing an apically directed acceleration of the myocardium. A substantial number of healthy subjects exhibit a second PSN spike predominantly at the level of the AA. Its mechanism remains to be elucidated.
在纵向心肌速度曲线上,收缩期末与舒张早期速度波起始之间的时间间隔内,可观察到一种以“切迹”为特征的独特速度模式。收缩期后速度切迹(PSN)的起源尚未明确。
对32名健康受试者进行高帧率心尖纵向轴彩色组织多普勒成像。
发现后主动脉壁(AW)、前间隔中部壁(MAS)和后二尖瓣环(MA)处PSN起始相对于前主动脉环(AA)的时间延迟显著长于零(5.1±2.2、6.0±2.3、6.8±2.8毫秒;p<0.001)。与AW、MAS和MA相比,AA处的幅度最高(4.77±1.28对2.88±1.11、2.15±0.73、2.44±1.17厘米/秒;p<0.001)。在研究对象中,10/32(31%)在AA处可识别出第二个PSN尖峰。其中,9例(28%)在AW处出现第二个PSN尖峰,3例(9%)在MAS处出现,MA处未出现。
AA是纵向速度曲线上PSN最早起始和最大幅度的部位,提示其机制是主动脉瓣关闭瞬间的能量释放导致心肌向心尖方向加速。相当数量的健康受试者主要在AA水平出现第二个PSN尖峰。其机制仍有待阐明。