Moorfields Eye Hospital, London, UK.
Moorfields Eye Hospital, London, UK Department of Experimental Medicine and Surgery, Ophthalmic Unit, University of Rome "Tor Vergata", Rome, Italy.
Br J Ophthalmol. 2014 Sep;98(9):1261-5. doi: 10.1136/bjophthalmol-2013-304579. Epub 2014 Apr 23.
To evaluate the clinical outcomes of phacoemulsification cataract surgery in microphthalmos.
Retrospective consecutive case series of eyes with axial length <20.9 mm, and requiring a high intraocular lens (IOL) power (≥30 or ≥35 dioptres for anterior or posterior chamber fixation, respectively), with no history of previous ocular surgery, and undergoing planned phacoemulsification cataract surgery with IOL implantation at Moorfields Eye Hospital was investigated to observe the incidence of intraoperative and postoperative complications.
During a 5-year study period, 47 of 22,093 eyes were treated in two locations (0.21%). Thirty-nine eyes met the study inclusion criteria. No serious intraoperative adverse events were recorded. Severe postoperative complications (retinal detachment and chronic postoperative uveitis) occurred in two cases. The postoperative corrected distance visual acuity (CDVA) was logMAR 0.30 or better in 24 eyes (62%), and only three eyes obtained worse vision. The overall ocular comorbitidy rate was 53%; 10 microphthalmic eyes (26%) presented with associated congenital or hereditary pathology, and had worse visual outcomes (p<0.0001).
Microphthalmic eyes requiring high IOL power are rare, and their presence is often associated with other ocular congenital or acquired disorders. Overall, the clinical outcomes were satisfactory and the surgical procedure affected by a low complication rate.
评估小眼球患者行超声乳化白内障吸除术的临床疗效。
回顾性连续病例系列研究纳入眼轴长度<20.9mm、需要高眼内晶状体(IOL)度数(前房或后房固定分别≥30 或≥35 屈光度)、无既往眼部手术史且计划行超声乳化白内障吸除术联合 IOL 植入术的患者,观察术中及术后并发症的发生率。
在 5 年的研究期间,22093 只眼中的 47 只(0.21%)在两个地点接受了治疗。39 只眼符合研究纳入标准。未记录到严重的术中不良事件。两例发生严重的术后并发症(视网膜脱离和慢性术后葡萄膜炎)。术后矫正视力(CDVA)达 logMAR 0.30 或更好的有 24 只眼(62%),仅有 3 只眼视力更差。总体眼部合并症发生率为 53%;10 只小眼球(26%)伴有先天性或遗传性疾病,视力结果更差(p<0.0001)。
需要高 IOL 度数的小眼球患者很少见,其存在通常与其他眼部先天性或获得性疾病有关。总体而言,临床疗效满意,手术并发症发生率低。