Vaneeva L I, Iankina N F, Ivanov A E, Razguliaeva O A, Zubov V P
Zh Mikrobiol Epidemiol Immunobiol. 1989 May(5):50-5.
The methods of the modification of Salmonella O- and H-antigens and the preparation of biologically active sorbents on their basis have been developed. The use of these sorbents has permitted the isolation of affinity antibodies with strictly defined specific activity. The work shows the possibility of the successful use of carriers obtained on the basis of porous glass, chemically modified by acrylic copolymers containing activated carboxylic groups, and intended for the immobilization of antigens of both protein and carbohydrate nature.
已经开发出修饰沙门氏菌O抗原和H抗原的方法,并在此基础上制备生物活性吸附剂。使用这些吸附剂能够分离出具有严格特定活性的亲和抗体。这项工作表明,成功使用基于多孔玻璃获得的载体是可能的,该载体经含有活化羧基的丙烯酸共聚物化学修饰,可用于固定蛋白质和碳水化合物性质的抗原。