Taylor C M, Kissun R D, Schor A M, McLeod D, Garner A, Weiss J B
Wolfson Angiogenesis Unit, Hope Hospital, Salford, England.
Invest Ophthalmol Vis Sci. 1989 Oct;30(10):2174-8.
The presence of endothelial cell-stimulating angiogenic factor (ESAF) in diseased human vitreous humour has been established. The molecular mass and chromatographic behavior of this material and its property of activating procollagenase indicate it to be identical to the ESAF isolated from other sources. The biological activity of ESAF from human vitreous was demonstrated by its ability to induce positive responses in the rabbit corneal pocket, and in the chick chorioallantoic membrane and yolk sac membrane tests.
已证实病变人类玻璃体液中存在内皮细胞刺激血管生成因子（ESAF）。该物质的分子量、色谱行为及其激活原胶原酶的特性表明它与从其他来源分离的ESAF相同。人玻璃体中ESAF的生物活性通过其在兔角膜囊、鸡绒毛尿囊膜和卵黄囊膜试验中诱导阳性反应的能力得以证明。
