Bora Aydın, Alptekin Cem, Yavuz Alpaslan, Batur Abdussamet, Akdemir Zülküf, Berköz Mehmet
Faculty of Medicine, Department of Radiodiagnosis, Yuzuncu Yıl University, 65080, Van, Turkey,
Abdom Imaging. 2014 Dec;39(6):1153-61. doi: 10.1007/s00261-014-0146-5.
In this study, we aimed to investigate the impact of non-alcoholic hepatic steatosis on the liver volume. As investigating hepatic steatosis, we utilized computed tomography (CT) to determine the degree of steatosis and we utilized hepatobiliary ultrasonography (USG) for densitometry and correlation.
As hepatosteatosis group, 35 patients over 18 years of age and whose abdominal CT scans were requested by several clinics and performed routinely were included in this study, and as control group, 40 healthy subjects without hepatosteatosis (clinically and radiologically) and correlated with hepatosteatosis group in terms of age and gender were included in this study. CT densitometry and liver attenuation index (LAI) of all individuals who participated in our study were calculated, and contrast images of patients were transferred to CT-Volume Software (Siemens Syngo Multimodality Workplace; Version VE52A). In this study, interactive and automated volume measurement techniques were used together. The volumes were measured separately in patient and control group.
In this study for each stage in USG, there was found a direct correlation in terms of LAI and volume, and this correlation was statistically significant (p < 0.01). Furthermore, statistical significance between size and USG stage draws attention (p < 0.05). A significance relationship between USG stage and age could not be determined.
As a result, we have reached the conclusion that CT densitometry can be used as an assistive technique along with USG to determine the degree of steatosis in the non-alcoholic fatty liver disease, and there is a positive linear correlation between the liver size and volume, and liver volume increases in the non-alcoholic fatty liver disease.
在本研究中,我们旨在探讨非酒精性肝脂肪变性对肝脏体积的影响。在研究肝脂肪变性时,我们利用计算机断层扫描(CT)来确定脂肪变性的程度,并利用肝胆超声检查(USG)进行密度测定及相关性分析。
作为肝脂肪变性组,本研究纳入了35名年龄超过18岁、由多家诊所要求并常规进行腹部CT扫描的患者;作为对照组,纳入了40名无肝脂肪变性(临床及放射学检查均无)且在年龄和性别上与肝脂肪变性组相匹配的健康受试者。计算了所有参与本研究个体的CT密度测定值及肝脏衰减指数(LAI),并将患者的对比图像传输至CT-Volume软件(西门子Syngo多模态工作站;版本VE52A)。在本研究中,交互式和自动体积测量技术结合使用。分别对患者组和对照组进行体积测量。
在本研究中,对于USG的每个阶段,在LAI和体积方面均发现存在直接相关性,且这种相关性具有统计学意义(p < 0.01)。此外,大小与USG阶段之间的统计学意义值得关注(p < 0.05)。无法确定USG阶段与年龄之间存在显著关系。
因此,我们得出结论,CT密度测定可作为一种辅助技术与USG一起用于确定非酒精性脂肪性肝病中的脂肪变性程度,肝脏大小与体积之间存在正线性相关性,且非酒精性脂肪性肝病中肝脏体积会增加。