Sharma Sonali, Dinkar Ajit D, Bedi Sumit
Senior Lecturer, Department of Oral Medicine and Radiology, Seema Dental College and Hospital , Veerbhadra Road, Rishikesh, Uttarakhand, India .
Professor and Head, Department of Oral Medicine and Radiology, Goa Dental College and Hospital , Bambolim, Goa, India .
J Clin Diagn Res. 2014 Mar;8(3):233-5. doi: 10.7860/JCDR/2014/7729.4171. Epub 2014 Mar 15.
Teeth form an excellent material for anthropological, genetic, odontologic and forensic investigations. The aim of this study was to establish the genetic control of sexual dimorphism in tooth size amongst siblings of Goan children in age range of 14-22 years.
Twenty-two sibling pairs were selected (22 males and 22 females) to assess genetic control of sexual dimorphism in tooth size. Alginate impressions were obtained for maxillary and mandibular arches and study models were prepared. Measurements were done using Zoom Digimatic Vernier Calipers with a resolution of 0.01 mm.
Correlation between mesiodistal and buccolingual tooth sizes amongst siblings was calculated using Pearson's correlation coefficient.
A statistically significant association was found between Mesiodistal Widths of Permanent Maxillary Right and Left Second Molars and between Maxillary Right and Left First Premolars amongst sibling pairs. A statistically significant association was also found between Buccolingual Widths of Mandibular Right and Left First Premolars amongst sibling pairs. This statistically significant correlation found amongst siblings establishes a genetic control over sexual dimorphism in these teeth.
The genetic basis of sexual dimorphism in human dentition was ascertained as a significant correlation was found between mesio-distal and bucco-lingual widths of premolars between sibling pairs.
牙齿是人类学、遗传学、牙科学和法医学研究的优质材料。本研究的目的是确定14至22岁果阿儿童同胞中牙齿大小性别二态性的遗传控制因素。
选择22对同胞(22名男性和22名女性)来评估牙齿大小性别二态性的遗传控制因素。获取上颌和下颌牙弓的藻酸盐印模并制作研究模型。使用分辨率为0.01毫米的Zoom数显卡尺进行测量。
使用Pearson相关系数计算同胞中近远中向和颊舌向牙齿大小之间的相关性。
在同胞对中,永久性上颌左右第二磨牙的近远中宽度之间以及上颌左右第一前磨牙之间发现了具有统计学意义的关联。在同胞对中,下颌左右第一前磨牙的颊舌宽度之间也发现了具有统计学意义的关联。在同胞中发现的这种具有统计学意义的相关性确立了对这些牙齿性别二态性的遗传控制。
人类牙列性别二态性的遗传基础已得到确定,因为在同胞对中前磨牙的近远中宽度和颊舌宽度之间发现了显著相关性。