National Development and Research Institutes, Inc., New York, NY.
Emory University, Rollins School of Public Health, Atlanta, GA.
Public Health Rep. 2014 May;129(3):267-79. doi: 10.1177/003335491412900309.
We estimated race/ethnicity-specific incident AIDS diagnosis rates (IARs) among people who inject drugs (PWID) in U.S. metropolitan statistical areas (MSAs) over time to assess the change in disparities after highly active antiretroviral therapy (HAART) dissemination.
We compared IARs and 95% confidence intervals (CIs) for black/African American and Hispanic/Latino PWID with those of white PWID in 93 of the most populous MSAs. We selected two three-year periods from the years immediately preceding HAART (1993-1995) and the years with the most recent available data (2005-2007). To maximize stability, we aggregated data across three-year periods, and we aggregated data for black/African American and Hispanic/Latino PWID for most comparisons with data for white PWID. We assessed disparities by comparing IAR 95% CIs for overlap.
IARs were significantly higher for black/African American and Hispanic/Latino PWID than for white PWID in 81% of MSAs in 1993-1995 and 77% of MSAs in 2005-2007. MSAs where disparities became non-significant over time were concentrated in the West. Significant differences were more frequent in comparisons between black/African American and white PWID (85% of MSAs in 1993-1995, 79% of MSAs in 2005-2007) than in comparisons between Hispanic/Latino and white PWID (53% of MSAs in 1993-1995, 56% of MSAs in 2005-2007). IARs declined modestly across racial/ethnic groups in most MSAs.
AIDS diagnosis rates continue to be substantially higher for black/African American and Hispanic/Latino PWID than for white PWID in most large MSAs. This finding suggests a need for increased targeting of prevention and treatment programs, as well as research on MSA-level conditions that may serve to maintain the disparities.
我们评估了美国大都市统计区(MSA)中注射吸毒者(PWID)的种族/民族特异性艾滋病诊断率(IAR)随时间的变化,以评估高效抗逆转录病毒疗法(HAART)传播后差异的变化。
我们比较了黑人/非裔美国人和西班牙裔/拉丁裔 PWID 与白人 PWID 在 93 个人口最多的 MSA 中的 IAR 和 95%置信区间(CI)。我们从 HAART 之前的年份(1993-1995 年)和最近有数据的年份(2005-2007 年)中选择了两个三年期。为了最大限度地稳定数据,我们将三年期的数据进行了汇总,并且将黑人/非裔美国人和西班牙裔/拉丁裔 PWID 的数据与白人 PWID 的数据进行了汇总,以便进行大多数比较。我们通过比较重叠的 IAR 95%CI 来评估差异。
在 1993-1995 年和 2005-2007 年,黑人/非裔美国人和西班牙裔/拉丁裔 PWID 的 IAR 明显高于白人 PWID,在 81%的 MSA 和 77%的 MSA 中都是如此。随着时间的推移,差异变得不显著的 MSA 主要集中在西部。在黑人/非裔美国人和白人 PWID 之间的比较中(1993-1995 年的 85%的 MSA,2005-2007 年的 79%的 MSA),差异更为频繁,而在西班牙裔/拉丁裔和白人 PWID 之间的比较中(1993-1995 年的 53%的 MSA,2005-2007 年的 56%的 MSA)则更为频繁。在大多数 MSA 中,不同种族/民族群体的 IAR 都略有下降。
在大多数大型 MSA 中,黑人/非裔美国人和西班牙裔/拉丁裔 PWID 的艾滋病诊断率仍然明显高于白人 PWID。这一发现表明,需要加强针对预防和治疗方案的针对性,以及针对可能维持差异的 MSA 一级条件的研究。