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脑膜黑素细胞瘤:病例报告及文献综述

Meningeal melanocytoma: case report and literature review.

作者信息

Kraft Roverea Rodrigo, Dagnonia Carini, Gomes de Oliveiraa Godofredo, Sapellia Jaqueline

出版信息

Bol Asoc Med P R. 2014;106(1):30-2.

Abstract

We report a case of a 54-year-old female with progressive chronic pain in lower extremity, paraplegia and loss of function of the anal sphincter. MRI revealed an expansive solid intradural and intramedullar lesion located at the T6 to T9 levels. Histology of the lesion showed melanocytes with the results of immunohistochemistry consistent with a melanocytoma. Melanocytic tumors are rare tumors which present a diagnostic and management challenge for the modern neurosurgeon and neuro-oncologist since MRI and CT features are non-specific and there is scant data to standardise best strategic therapy.

摘要

我们报告一例54岁女性患者,患有进行性下肢慢性疼痛、截瘫及肛门括约肌功能丧失。磁共振成像(MRI)显示在T6至T9水平有一个硬膜内及髓内的实性膨胀性病变。病变的组织学检查显示有黑素细胞,免疫组化结果符合黑素细胞瘤。黑素细胞肿瘤是罕见肿瘤,对现代神经外科医生和神经肿瘤学家而言,其诊断和治疗颇具挑战,因为MRI和CT表现不具特异性,且缺乏标准化最佳治疗策略的数据。

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