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“为什么我总是看到重影?”一例误诊10年的眼肌型重症肌无力病例。

"Why do I always see double?" A misdiagnosed case of ocular myasthenia gravis for 10 years.

作者信息

Yousuf Uduman Ali Mohamed, Yashodhara B M, Thanigasalam Thevi, Ting Heng Siang

机构信息

Department of Medicine, Melaka Manipal Medical College, Melaka, Malaysia.

出版信息

BMJ Case Rep. 2014 May 2;2014:bcr2013203488. doi: 10.1136/bcr-2013-203488.

Abstract

A 58-year-old man presented with diplopia and partial ptosis for 10 years. It was non-progressive in nature, despite inadequate medical attention the patient received from non-specialists/general practitioners. He did not have fatigability or diurnal variation in weakness and was clinically stable without exacerbations of disease for a decade. He did not have features of Graves's disease, oculopharyngeal dystrophy, cranial nerve paralysis, polymyositis and stroke. The possibility of an atypical presentation of myasthenia gravis (MG) was considered and the patient was evaluated. Ice pack test was negative, Cogan's lid twitch (CLT) test was positive and high titres of acetylcholine receptor antibodies (AChR Ab) suggestive of MG were found. He was treated accordingly with a very good response.

摘要

一名58岁男性,出现复视和部分上睑下垂10年。尽管患者从非专科医生/全科医生那里得到的医疗关注不足,但病情本质上无进展。他没有疲劳感,肌无力也无日间变化,临床稳定,十年间病情未加重。他没有格雷夫斯病、眼咽型肌营养不良、颅神经麻痹、多发性肌炎和中风的特征。考虑到重症肌无力(MG)非典型表现的可能性,对该患者进行了评估。冰袋试验阴性,科根眼睑抽搐(CLT)试验阳性,发现高滴度的乙酰胆碱受体抗体(AChR Ab)提示MG。给予相应治疗后反应良好。

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