具有上转换发光特性的量子点在生物成像中的应用。

Applications of quantum dots with upconverting luminescence in bioimaging.

作者信息

Chen Yunyun, Liang Hong

机构信息

Materials Science and Mechanical Engineering, Texas A&M University, College Station, TX 77843-3123, USA.

Materials Science and Mechanical Engineering, Texas A&M University, College Station, TX 77843-3123, USA; Department of Mechanical Engineering, Texas A&M University, College Station, TX 77843-3123, USA.

出版信息

J Photochem Photobiol B. 2014 Jun 5;135:23-32. doi: 10.1016/j.jphotobiol.2014.04.003. Epub 2014 Apr 18.

DOI:10.1016/j.jphotobiol.2014.04.003

PMID:24792570

Abstract

Quantum dots (QDs) have attracted great attention in recent years due to their promising applications in bioimaging. Compared with traditional ultraviolet excitation of QDs, near-infrared laser (NIR) excitation has many advantages, such as being less harmful, little blinking effects, zero autofluorescence and deep penetration in tissue. Composing QDs with upconverting properties is promising to enable NIR excitation. This article provides a review of QDs with upconverting luminescence and their applications in bioimaging. Based on the mechanisms of luminescence, discussion will be divided into four groups: nanoheterostructures/mixtures of QDs and upconverting nanoparticles, graphene quantum dots, lanthanide-doped QDs, and double QDs. The content includes synthetic routes, upconverting luminescence properties, and their applications in bioimaging.

摘要

近年来，量子点（QDs）因其在生物成像方面的潜在应用而备受关注。与传统的量子点紫外激发相比，近红外激光（NIR）激发具有许多优点，如危害较小、闪烁效应小、自发荧光为零以及在组织中穿透深度大。将具有上转换特性的量子点组合有望实现近红外激发。本文综述了具有上转换发光的量子点及其在生物成像中的应用。基于发光机制，讨论将分为四组：量子点与上转换纳米粒子的纳米异质结构/混合物、石墨烯量子点、镧系掺杂量子点和双量子点。内容包括合成路线、上转换发光特性及其在生物成像中的应用。