Islam Shofiq, Uwadiae Nosa, Ormiston Ian W
Department of Maxillofacial Surgery, Leicester Royal Infirmary, Infirmary Square, Leicester, East Midlands LE1 5WW, UK.
Department of Maxillofacial Surgery, Leicester Royal Infirmary, Infirmary Square, Leicester, East Midlands LE1 5WW, UK.
Br J Oral Maxillofac Surg. 2014 Jul;52(6):496-500. doi: 10.1016/j.bjoms.2014.04.002. Epub 2014 May 1.
In the United Kingdom, maxillofacial techniques are underused in the treatment of obstructive sleep apnoea (OSA). We retrospectively analysed the details and relevant clinical data of consecutive patients who had operations for OSA at the maxillofacial unit in Leicester between 2002 and 2012. They had been referred from the local sleep clinic after investigation and diagnosis, and in all cases treatment with continuous positive airway pressure (CPAP) had failed. We compared preoperative and postoperative apnoea/hypopnoea indices (AHI), scores for the Epworth sleepiness scale (ESS), and lowest oxygen saturation to measure surgical success (AHI of less than 15 and a 50% reduction in the number of apnoeas or hypopnoea/hour) and surgical cure (AHI of less than 5). We identified 51 patients (mean age 44 years, range 21-60) with a mean (SD) body mass index (BMI) of 29 (3.4). Most patients had bimaxillary advancement with genioplasty (n=42). Differences in mean (SD) preoperative and postoperative values were significant for all 3 outcome measures (AHI: 42 (17) to 8 (7) p<0.001; ESS: 14 (4) to 5 (4) p<0.001; lowest oxygen saturation: 76% (11%) to 83% (7%); p=0.006). On the postoperative sleep study 85% of patients met the criteria for surgical success. Our experience has confirmed that bimaxillary advancement results in a high rate of success in patients with OSA. The operation has a role in the management of selected patients in the UK who do not adhere to CPAP.
在英国,颌面技术在阻塞性睡眠呼吸暂停(OSA)的治疗中未得到充分利用。我们回顾性分析了2002年至2012年间在莱斯特颌面科接受OSA手术的连续患者的详细信息和相关临床数据。他们在经过调查和诊断后从当地睡眠诊所转诊而来,并且在所有病例中持续气道正压通气(CPAP)治疗均失败。我们比较了术前和术后的呼吸暂停/低通气指数(AHI)、爱泼华嗜睡量表(ESS)得分以及最低血氧饱和度,以衡量手术成功率(AHI小于15且呼吸暂停或低通气次数/小时减少50%)和手术治愈率(AHI小于5)。我们确定了51例患者(平均年龄44岁,范围21 - 60岁),平均(标准差)体重指数(BMI)为29(3.4)。大多数患者接受了双颌前徙术加颏成形术(n = 42)。所有3项结局指标的术前和术后平均(标准差)值差异均有统计学意义(AHI:42(17)至8(7),p < 0.001;ESS:14(4)至5(4),p < 0.001;最低血氧饱和度:76%(11%)至83%(7%);p = 0.006)。在术后睡眠研究中,85%的患者达到了手术成功标准。我们的经验证实,双颌前徙术在OSA患者中成功率很高。该手术在英国对不坚持使用CPAP的特定患者的管理中具有作用。