Anesthesiology and Intensive Care Medicine, Karadeniz Technical University, 61080 Trabzon, Turkey.
Biomed Res Int. 2014;2014:938108. doi: 10.1155/2014/938108. Epub 2014 Mar 31.
Comparison of dexketoprofen and paracetamol added to the lidocaine in Regional Intravenous Anesthesia in terms of hemodynamic effects, motor and sensorial block onset times, intraoperative VAS values, and analgesia requirements.
The files of 73 patients between 18 and 65 years old in the ASA I-II risk group who underwent hand and forearm surgery were analyzed and 60 patients were included in the study. Patients were divided into 3 groups: Group D (n = 20), 3 mg/kg 2% lidocaine and 50 mg/2 mL dexketoprofen trometamol; Group P (n = 20), 3 mg/kg 2% lidocaine and 3 mg/kg paracetamol; Group K (n = 20), 3 mg/kg 2% lidocaine. Demographic data, motor and sensorial block times, heart rate, mean blood pressure, VAS values, and intraoperative and postoperative analgesia requirements were recorded.
Sensorial and motor block onset durations of Group K were significantly longer than other groups. Motor block termination duration was found to be significantly longer in Group D than in Group K. VAS values of Group K were found higher than other groups. There was no significant difference in VAS values between Group D and Group P. Analgesia requirement was found to be significantly more in Group K than in Group P. There was no significant difference between the groups in terms of heart rates and mean arterial pressures.
We concluded that the addition of 3 mg/kg paracetamol and 50 mg dexketoprofen to lidocaine as adjuvant in Regional Intravenous Anesthesia applied for hand and/or forearm surgery created a significant difference clinically.
比较在局部静脉麻醉中加入右酮洛芬和对乙酰氨基酚与利多卡因相比,对血流动力学的影响、运动和感觉阻滞的起始时间、术中 VAS 值和镇痛需求。
分析了年龄在 18 至 65 岁之间、ASA I-II 风险组的 73 名患者的病历,其中 60 名患者纳入研究。患者分为 3 组:D 组(n = 20),3mg/kg 2%利多卡因和 50mg/2ml 右酮洛芬托美他醇;P 组(n = 20),3mg/kg 2%利多卡因和 3mg/kg 对乙酰氨基酚;K 组(n = 20),3mg/kg 2%利多卡因。记录人口统计学数据、运动和感觉阻滞时间、心率、平均血压、VAS 值以及术中术后镇痛需求。
K 组感觉和运动阻滞的起始时间明显长于其他组。D 组的运动阻滞终止时间明显长于 K 组。K 组的 VAS 值明显高于其他组。D 组和 P 组的 VAS 值没有显著差异。K 组的镇痛需求明显高于 P 组。心率和平均动脉压在各组之间没有显著差异。
我们得出的结论是,在用于手部和/或前臂手术的局部静脉麻醉中,加入 3mg/kg 对乙酰氨基酚和 50mg 右酮洛芬与利多卡因作为佐剂在临床上有显著差异。