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脑囊尾蚴病(作者译)

[Cysticercosis of the brain (author's transl)].

作者信息

Ronge J, Aidoo G A, Krüger G

出版信息

Fortschr Neurol Psychiatr Grenzgeb. 1978 May;46(5):269-86.

PMID:248042
Abstract

Two cases of cysticercosis of the brain with multilocular parasite infestation are reported. Case 1 showed temporal lobe epilepsy with corresponding EEG and parkinsonism. Pathomorphologically there were parasites in the sylvian fossa and a bilateral necrosis of the pallidum. In case 2 there was a cranial nerve deficit (n.vestibulo-cochlearis) with pronounced vestibular ataxia. Parasite vesicles were surgically removed from the cerebello-pontine angle. Neurohistologically, chronic inflammatory changes were present in the immediate vicinity of the parasite. In both cases there was cysticercosis of the rhomboid fossa and base of the brain (leptomeningitis) with evidence of a process of the posterior cranial fossa. Psychic changes (hysteriform behavioral abnormalities, psychotic episodes and, increasingly, an organic psychosyndrome) were observed particularly in case 1. This case was followed for 11 years on the basis of documented and personal investigations. This report discusses the differential diagnosis and therapy of brain cysticercosis with reference to the two cases and the literature.

摘要

报告了两例脑囊尾蚴病合并多房寄生虫感染的病例。病例1表现为颞叶癫痫伴相应脑电图改变及帕金森综合征。病理形态学显示,大脑外侧裂池有寄生虫,苍白球双侧坏死。病例2有颅神经缺损(前庭蜗神经),伴有明显的前庭共济失调。寄生虫囊泡经手术从桥小脑角取出。神经组织学检查发现,寄生虫紧邻部位有慢性炎症改变。两例均有菱形窝和脑底部的囊尾蚴病(软脑膜炎),有后颅窝病变的证据。特别是在病例1中观察到精神改变(癔症样行为异常、精神病发作,且越来越多地出现器质性精神综合征)。基于文献记载和个人调查,该病例随访了11年。本报告结合这两个病例及文献讨论了脑囊尾蚴病的鉴别诊断和治疗。

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