Aribas Alpay, Keskin Suat, Akilli Hakan, Kayrak Mehmet, Erdogan Halil Ibrahim, Guler Ibrahim, Yildirim Oguzhan, Bekci Taha Tahir
Department of Cardiology, Necmettin Erbakan University Meram School of Medicine Hospital, Meram, 42080, Konya, Turkey,
Jpn J Radiol. 2014 Aug;32(8):451-60. doi: 10.1007/s11604-014-0327-8. Epub 2014 May 13.
To evaluate the accuracy of cardiac computed tomography (CT) parameters and pulmonary artery (PA) obstruction (OS) scores in determining the echocardiographic right ventricular dysfunction (RVD) in hemodynamically stable patients with acute pulmonary embolism (PE).
A total of 120 patients with acute PE were included in the study. Right ventricle/left ventricle ratio (RV/LV); PA axial diameter; superior vena cava (SVC) axial diameter; and Ghanima, Miller, Qanadli, and Mastora obstruction scores were obtained using CT. RVD was assessed by echocardiography. The patients were divided into two groups based on the presence or absence of RVD.
RV/LV ratio, SVC axial diameter, PA axial diameter, and Miller, Qanadli, and Mastora scores were significantly increased in the RVD group. Multivariate logistic regression analysis showed that RV/LV ratio [OR 6.36 (2.02-279.46 95 % CI), p = 0.01] and PA axial diameter [OR 5.02 (1.02-1.26 95 % CI), p = 0.03] were independent predictors of echocardiographic RVD. Predictive values of these parameters were improved when combined with other intragroup cutoff values. A cutoff value for the RV/LV ratio of >1.08 had 81.43 % sensitivity, 52.08 % specificity, 71.3 PPV, and 65.8 NPV for prediction of RVD.
Tomographic axial diameters enable more accurate predictions of RVD than OS scores do.
评估心脏计算机断层扫描(CT)参数和肺动脉(PA)阻塞(OS)评分在确定血流动力学稳定的急性肺栓塞(PE)患者超声心动图右心室功能障碍(RVD)方面的准确性。
本研究共纳入120例急性PE患者。使用CT获取右心室/左心室比值(RV/LV)、PA轴径、上腔静脉(SVC)轴径以及加尼马、米勒、卡纳迪和马托拉阻塞评分。通过超声心动图评估RVD。根据是否存在RVD将患者分为两组。
RVD组的RV/LV比值、SVC轴径、PA轴径以及米勒、卡纳迪和马托拉评分显著升高。多因素逻辑回归分析显示,RV/LV比值[比值比(OR)6.36(2.02 - 279.46,95%置信区间),p = 0.01]和PA轴径[OR 5.02(1.02 - 1.26,95%置信区间),p = 0.03]是超声心动图RVD的独立预测因素。当与其他组内临界值结合时,这些参数的预测价值得到提高。RV/LV比值>1.08的临界值预测RVD的敏感性为81.43%,特异性为52.08%,阳性预测值为71.3%,阴性预测值为65.8%。
断层轴径比OS评分能够更准确地预测RVD。