Baird Christopher W, Myers Patrick O, Borisuk Michele, Kalish Brian, Hofferberth Sophie, Nathan Meena, Emani Sitaram M, del Nido Pedro J
Department of Cardiac Surgery, Boston Children's Hospital and Harvard Medical School, Boston, Mass.
Department of Cardiac Surgery, Boston Children's Hospital and Harvard Medical School, Boston, Mass; Division of Cardiovascular Surgery, Geneva University Hospitals and School of Medicine, Geneva, Switzerland.
J Thorac Cardiovasc Surg. 2014 Oct;148(4):1506-11. doi: 10.1016/j.jtcvs.2014.04.018. Epub 2014 Apr 13.
With advances in valve repair and ventricular recruitment strategies, patients initially palliated with single ventricle physiology have been increasingly brought to biventricular circulation. Few data are available on the technical aspects and outcomes after takedown of the superior cavopulmonary anastomosis (bidirectional Glenn [BDG]). We reviewed a single-institutional experience in BDG takedown.
The demographic, procedural, and outcome data were obtained for all children who had undergone BDG takedown at our institution from 2000 to 2012. The primary outcome measures were achievement of biventricular circulation, reoperation, and mortality. The secondary outcome measures were postoperative arrhythmias, superior vena cava (SVC)-right atrium (RA) or pulmonary artery stenosis at the BDG takedown site.
A total of 40 patients were included during the study period, with a mean age of 4.4 years (range, 7 months to 22 years). Primary SVC-RA anastomosis was performed in 7 patients (18%), and an anterior patch was used in 33 patients (82%). Of the 40 patients, 38 were discharged with biventricular physiology (98%) and mild or less ventricular dysfunction. During a mean follow-up period of 3.4±2.9 years, 3 patients died and 1 required heart transplantation; 2 patients developed more than mild SVC stenosis requiring reintervention and 1 developed pulmonary artery stenosis. Finally, 34 patients were in normal sinus rhythm and 4 had heart block (1 pacemaker placement).
BDG takedown can be undertaken with a low operative risk and a low incidence of SVC or pulmonary artery stenosis or sinus node dysfunction. Additional follow-up is required to see how the reconstructed SVC grows.
随着瓣膜修复和心室募集策略的进展,最初采用单心室生理姑息治疗的患者越来越多地实现了双心室循环。关于上腔静脉肺动脉吻合术(双向格林分流术[BDG])拆除后的技术细节和结果,相关数据较少。我们回顾了在单一机构进行BDG拆除的经验。
获取了2000年至2012年在本机构接受BDG拆除的所有儿童的人口统计学、手术过程和结果数据。主要结局指标为实现双心室循环、再次手术和死亡率。次要结局指标为术后心律失常、BDG拆除部位的上腔静脉(SVC)-右心房(RA)或肺动脉狭窄。
研究期间共纳入40例患者,平均年龄4.4岁(范围7个月至22岁)。7例患者(18%)进行了原发性SVC-RA吻合,33例患者(82%)使用了前补片。40例患者中,38例出院时具有双心室生理功能(98%)且心室功能障碍为轻度或更轻。在平均3.4±2.9年的随访期内,3例患者死亡,1例需要心脏移植;2例患者出现了超过轻度的SVC狭窄需要再次干预,1例出现了肺动脉狭窄。最后,34例患者为正常窦性心律,4例有心脏传导阻滞(1例植入起搏器)。
BDG拆除手术风险低,SVC或肺动脉狭窄或窦房结功能障碍的发生率低。需要进一步随访以观察重建的SVC如何生长。