Zhang Ning, Guo Liemei, Ge Jianwei, Qiu Yongming
From the *Department of Neurosurgery, Shanghai Fengxian District Central Hospital, Shanghai Jiao Tong University Affiliated Sixth People's Hospital South Campus; and †Department of Neurosurgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
J Craniofac Surg. 2014 May;25(3):e271-2. doi: 10.1097/SCS.0000000000000632.
Bromocriptine has been the most widely used and effective agent to treat macroprolactinoma, and chiasmal herniation in a macroprolactinoma patient following the treatment with bromocriptine is a well-recognized complication. However, herniation of the inferior mesial frontal lobe into the sella has been rarely reported. The present clinical report is the second radiographic demonstration of herniation of the inferior mesial frontal lobe into the sella. After the treatment with transsphenoidal endoscopic chiasmopexy, the patient's visual disturbance improved dramatically. We suggest that transsphenoidal endoscopic chiasmopexy is an effective treatment option for the prolactinoma patient with brain and chiasmal herniations following the treatment with bromocriptine.
溴隐亭一直是治疗大泌乳素瘤最广泛使用且有效的药物,而大泌乳素瘤患者在接受溴隐亭治疗后发生视交叉疝是一种广为人知的并发症。然而,内侧额叶下部疝入蝶鞍的情况鲜有报道。本临床报告是内侧额叶下部疝入蝶鞍的第二例影像学证实。经蝶窦内镜视交叉固定术后,患者的视觉障碍显著改善。我们认为,经蝶窦内镜视交叉固定术是溴隐亭治疗后出现脑疝和视交叉疝的泌乳素瘤患者的有效治疗选择。