Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL.
Department of Preventive Medicine and OB/GYN, Northwestern University Medical Center, Chicago, IL.
Am J Geriatr Psychiatry. 2014 Jun;22(6):598-605. doi: 10.1016/j.jagp.2012.11.004. Epub 2013 Apr 6.
This study aimed to examine the longitudinal association between decline in cognitive function and elder mistreatment (EM).
Chicago Health and Aging Project (CHAP) is an epidemiologic study conducted in a geographically defined community (N = 6,159). We identified 143 CHAP participants who had longitudinal cognitive data and EM reported to social services agency. The primary predictor was cognitive function, which was assessed using the Mini-Mental State Examination (MMSE), the Symbol Digit Modalities Test (Perceptual Speed), and both immediate and delayed recall of the East Boston Memory Test (Episodic Memory). An index of global cognitive function scores was derived by averaging z scores of all tests. Logistic regression models were used to assess the association of cognitive function domains and risk for EM.
After adjusting for potential confounders, every one-point decline in global cognitive function (odds ratio [OR]: 1.57 [1.21-2.03]), MMSE (OR: 1.07 [1.03-1.10]), Episodic Memory (OR: 1.46 [1.14-1.86]), and Perceptual Speed (OR: 1.05 [1.02-1.07]) scores were associated with increased risk for EM. Lowest tertiles in global cognitive function (OR: 2.71 [1.49-4.88]), MMSE (OR: 2.02 [1.07-3.80]), Episodic Memory (OR: 2.70 [1.41-5.16]), and Perceptual Speed (OR: 4.41 [2.22-8.76]) scores were associated with increased risk for EM.
Decline in global cognitive function, MMSE, and Perceptual Speed scores were associated with increased risk for EM.
本研究旨在探讨认知功能下降与老年虐待(EM)之间的纵向关联。
芝加哥健康与老龄化项目(CHAP)是一项在地理上界定的社区(N=6159)中进行的流行病学研究。我们确定了 143 名 CHAP 参与者,他们具有纵向认知数据和向社会服务机构报告的 EM。主要预测指标是认知功能,使用简易精神状态检查(MMSE)、符号数字模态测试(知觉速度)以及东波士顿记忆测试的即时和延迟回忆(情景记忆)来评估。通过平均所有测试的 z 分数得出全球认知功能得分指数。使用逻辑回归模型评估认知功能领域与 EM 风险之间的关联。
在调整潜在混杂因素后,全球认知功能(优势比[OR]:1.57[1.21-2.03])、MMSE(OR:1.07[1.03-1.10])、情景记忆(OR:1.46[1.14-1.86])和知觉速度(OR:1.05[1.02-1.07])每下降一个点,EM 的风险就会增加。全球认知功能最低三分位数(OR:2.71[1.49-4.88])、MMSE(OR:2.02[1.07-3.80])、情景记忆(OR:2.70[1.41-5.16])和知觉速度(OR:4.41[2.22-8.76])得分与 EM 风险增加相关。
全球认知功能、MMSE 和知觉速度得分下降与 EM 风险增加相关。