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针对初级保健医生信息需求的全国性调查:雄激素剥夺治疗患者的副作用管理

National survey addressing the information needs of primary care physicians: Side effect management of patients on androgen deprivation therapy.

作者信息

Soeyonggo Tony, Locke Jennifer, Giudice Maria Elizabeth Del, Alibhai Shabbir, Fleshner Neil Eric, Warde Padraig

机构信息

Department of Family Medicine, Queen's University, Kingston, ON;

Faculty of Medicine, University of Toronto, Toronto, ON;

出版信息

Can Urol Assoc J. 2014 Mar;8(3-4):E227-34. doi: 10.5489/cuaj.1015.

Abstract

OBJECTIVE

Androgen deprivation therapy (ADT) is a common treatment for prostate cancer with numerous side effects. We assess primary care physicians' (PCPs) knowledge of ADT side effects and their interest in increasing their knowledge in this area.

METHODS

A list of active Canadian PCPs was obtained using the Canadian Medical Directory. A cross-sectional survey was distributed to 600 randomly selected physicians. We collected PCPs' demographic information, experience with ADT management, knowledge regarding ADT side effects and desired sources for obtaining knowledge on ADT management.

RESULTS

In total, we received 103 completed questionnaires. Of these, 89% of PCPs had patients on ADT. One-third of respondents prescribed ADT and over half of them administered ADT annually. Thirty-eight percent felt their knowledge of ADT side effects was inadequate and 50% felt uncomfortable counselling patients on ADT. Many PCPs were less familiar with the incidence of functional side effects of ADT (i.e., hot flashes, fatigue and erectile dysfunction) compared to life-threatening side effects (i.e., cardiovascular events, metabolic syndrome, fractures). In terms of increasing their knowledge of ADT side effects, 82% of PCPs would use educational resources if they were available (52% and 32% preferred continued medical education [CME] events and educational pamphlets, respectively).

CONCLUSIONS

PCPs play an important role in managing ADT side effects. There is poor awareness of the prevalence of ADT side effects, and many are uncomfortable in managing these side effects. These areas may be addressed through CME programs and educational pamphlets.

摘要

目的

雄激素剥夺疗法(ADT)是前列腺癌的一种常见治疗方法,但有许多副作用。我们评估基层医疗医生(PCP)对ADT副作用的了解程度以及他们对增加该领域知识的兴趣。

方法

使用《加拿大医学名录》获取加拿大在职PCP的名单。向600名随机选择的医生发放了横断面调查问卷。我们收集了PCP的人口统计学信息、ADT管理经验、关于ADT副作用的知识以及获取ADT管理知识的期望来源。

结果

我们总共收到了103份完整的问卷。其中,89%的PCP有接受ADT治疗的患者。三分之一的受访者开具ADT处方,其中超过一半的人每年进行ADT治疗。38%的人认为他们对ADT副作用的了解不足,50%的人在为患者提供ADT咨询时感到不自在。与危及生命的副作用(即心血管事件、代谢综合征、骨折)相比,许多PCP对ADT功能性副作用(即潮热、疲劳和勃起功能障碍)的发生率了解较少。在增加对ADT副作用的了解方面,如果有可用的教育资源,82%的PCP会使用(分别有52%和32%的人更喜欢继续医学教育[CME]活动和教育手册)。

结论

PCP在管理ADT副作用方面发挥着重要作用。对ADT副作用的患病率认识不足,许多人在管理这些副作用时感到不自在。这些方面可以通过CME项目和教育手册来解决。

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