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Treatment-refractory OCD responding to maintenance electroconvulsive therapy.难治性强迫症对维持性电休克治疗有反应。
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Electroconvulsive therapy reduces frontal cortical connectivity in severe depressive disorder.电抽搐疗法可降低重度抑郁障碍患者的额皮质连接。
Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5464-8. doi: 10.1073/pnas.1117206109. Epub 2012 Mar 19.
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Treatment-refractory obsessive-compulsive disorder: methodological issues, operational definitions and therapeutic lines.难治性强迫症:方法学问题、操作定义及治疗方法
Prog Neuropsychopharmacol Biol Psychiatry. 2006 May;30(3):400-12. doi: 10.1016/j.pnpbp.2005.11.028. Epub 2006 Feb 28.
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Obsessive-compulsive disorder, the brain and electroconvulsive therapy.强迫症、大脑与电休克疗法
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Elevated thalamic and prefrontal regional cerebral blood flow in obsessive-compulsive disorder: a SPECT study.强迫症患者丘脑和前额叶区域脑血流量增加:一项单光子发射计算机断层扫描研究。
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The 1978 and 1990 APA Task Force Reports.1978年和1990年美国心理学会特别工作组报告。
Convuls Ther. 1990;6(2):79-81.
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Tc-99m HMPAO brain perfusion SPECT in drug-free obsessive-compulsive patients without depression.无抑郁的未用药强迫症患者的锝-99m六甲基丙二胺肟脑灌注单光子发射计算机断层扫描
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电抽搐治疗严重强迫症伴抑郁症状。

Electroconvulsive therapy on severe obsessive-compulsive disorder comorbid depressive symptoms.

机构信息

Department of Medical Psychology, Chinese PLA General Hospital & Medical School PLA, Beijing, China.

Department of Medical Psychology, Anhui Medical University, Hefei, Anhui, China.

出版信息

Psychiatry Investig. 2014 Apr;11(2):210-3. doi: 10.4306/pi.2014.11.2.210. Epub 2014 Apr 11.

DOI:10.4306/pi.2014.11.2.210
PMID:24843380
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4023099/
Abstract

Electroconvulsive therapy (ECT) is not currently used as a first-line treatment for obsessive-compulsive disorder (OCD). However, several related case reports have demonstrated that ECT seems to be effective for severe OCD, especially when first-line therapies have failed. In this study, we describe the courses, detailed parameters, effects, and follow-up information relating to three patients with severe OCD who were treated by modified bifrontal ECT after their first-line anti-OCD treatments pharmacotherapy, behavioral therapy, and cognitive behavioral therapy failed. The number of ECT procedures administered in each case is as follows: Case 1, eight; Case 2, three; and Case 3, four. In all three cases, the patients' depressive symptoms improved considerably after the ECT procedures. In addition, the condition of all three patients' OCD significantly improved and remained stable at regular follow-ups. ECT may play an effective role in treating severe OCD.

摘要

电抽搐治疗(ECT)目前不作为强迫症(OCD)的一线治疗方法。然而,几项相关的病例报告表明,ECT 似乎对严重的 OCD 有效,尤其是在一线治疗失败的情况下。在这项研究中,我们描述了三例严重 OCD 患者的病程、详细参数、疗效和随访信息,这些患者在一线抗 OCD 治疗(药物治疗、行为治疗和认知行为治疗)失败后接受了改良的双额 ECT 治疗。每个病例中 ECT 治疗的次数如下:病例 1,8 次;病例 2,3 次;病例 3,4 次。在所有三个病例中,ECT 治疗后患者的抑郁症状明显改善。此外,所有三个患者的 OCD 症状都显著改善,在定期随访时保持稳定。ECT 可能在治疗严重 OCD 方面发挥有效作用。