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三维打印技术在下颌角截骨术后骨缺损人工骨制备中的应用

[Application of three-dimensional printing technique in artificial bone fabrication for bone defect after mandibular angle ostectomy].

作者信息

Shen Congcong, Zhang Yan, Li Qingfeng, Zhu Ming, Hou Yikang, Qu Miao, Xu Yourong, Chai Gang

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2014 Mar;28(3):300-3.

PMID:24844008
Abstract

OBJECTIVE

To investigate the application of three-dimensional (3-D) printing technique combining with 3-D CT and computer aided-design technique in customized artificial bone fabrication, correcting mandibular asymmetry deformity after mandibular angle ostectomy.

METHODS

Between April 2011 and June 2013, 23 female patients with mandibular asymmetry deformity after mandibular angle ostectomy were treated. The mean age was 27 years (range, 22-34 years). The disease duration of mandibular asymmetry deformity was 6-16 months (mean, 12 months). According to the CT data and individualized mandibular angle was simulated based on mirror theory, 3-D printed implants were fabricated as the standard reference for manufacturers to fabricated artificial bone graft, and then mandible repair operation was performed utilizing the customized artificial bone to improve mandibular asymmetry.

RESULTS

The operation time varied from 40 to 60 minutes (mean, 50 minutes). Primary healing of incisions was obtained in all patients; no infection, hematoma, and difficulty in opening mouth occurred. All 23 patients were followed up 3-10 months (mean, 6.7 months). After operation, all patients obtained satisfactory facial and mandibular symmetry. 3-D CT reconstructive examination results after 3 months of operation showed good integration of the artificial bone.

CONCLUSION

3-D printing technique combined with 3-D CT and computer aided design technique can be a viable alternative to the approach of maxillofacial defects repair after mandibular angle ostectomy, which provides a accurate and easy way.

摘要

目的

探讨三维(3-D)打印技术结合三维CT及计算机辅助设计技术在定制人工骨制作及下颌角截骨术后下颌不对称畸形矫正中的应用。

方法

2011年4月至2013年6月,对23例下颌角截骨术后下颌不对称畸形的女性患者进行治疗。平均年龄27岁(范围22 - 34岁)。下颌不对称畸形病程6 - 16个月(平均12个月)。根据CT数据,基于镜像理论模拟个体化下颌角,制作3-D打印植入物作为厂家制作人工骨 graft的标准参考,然后采用定制人工骨进行下颌骨修复手术以改善下颌不对称。

结果

手术时间40 - 60分钟(平均50分钟)。所有患者切口均一期愈合;未发生感染、血肿及张口困难。23例患者均获随访3 - 10个月(平均6.7个月)。术后所有患者面部及下颌对称性均获满意效果。术后3个月的三维CT重建检查结果显示人工骨融合良好。

结论

三维打印技术结合三维CT及计算机辅助设计技术可成为下颌角截骨术后颌面部缺损修复方法的一种可行替代方案,提供了一种准确且简便的方法。

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