Gorka Stephanie M, Shankman Stewart A, Olino Thomas M, Seeley John R, Kosty Derek B, Lewinsohn Peter M
University of Illinois at Chicago, Department of Psychology, 1007 West Harrison Street (M/C 285), Chicago, IL 60657, United States.
University of Illinois at Chicago, Department of Psychology, 1007 West Harrison Street (M/C 285), Chicago, IL 60657, United States.
Drug Alcohol Depend. 2014 Jul 1;140:191-7. doi: 10.1016/j.drugalcdep.2014.04.021. Epub 2014 May 4.
There have been mixed findings on the temporal relation between anxiety disorders and alcohol use disorders (AUDs), suggesting that the pathway to AUDs may differ among individuals. The aim of the current study was to test whether parental support moderated the association between anxiety disorders and the development of AUDs. We also tested whether our effects differed as a function of age of AUD onset.
817 individuals were assessed for lifetime diagnoses of psychopathology during 4-waves between adolescence (mean age=16) and adulthood (mean age=30).
Proportional hazards model analyses indicated that baseline anxiety disorders interacted with baseline perceived maternal support to prospectively predict onset of AUDs. At high levels of maternal support, anxiety disorders were associated with a reduced risk for AUD onset (HR=0.74, 95% CI=0.55-1.00). However, this effect was more robust for AUDs that developed prior to age 20. At low levels of maternal support, anxiety disorders were associated with an increased risk for AUD onset (HR=1.65, 95% CI=1.21-2.26). This effect was present for AUDs that developed across adolescence and adulthood. Paternal support was not associated with AUDs and did not interact with anxiety disorders.
Prevention and intervention efforts targeted at maternal support in adolescents with anxiety disorders may be valuable, as this may represent a factor that has a significant impact on the developmental course of AUDs.
关于焦虑症与酒精使用障碍(AUDs)之间的时间关系,研究结果不一,这表明导致 AUDs 的途径可能因人而异。本研究的目的是检验父母支持是否会调节焦虑症与 AUDs 发展之间的关联。我们还检验了这种影响是否因 AUD 发病年龄而异。
对 817 名个体在青春期(平均年龄 = 16 岁)至成年期(平均年龄 = 30 岁)的 4 个阶段进行了终生精神病理学诊断评估。
比例风险模型分析表明,基线焦虑症与基线感知到的母亲支持相互作用,可前瞻性预测 AUDs 的发病。在高水平的母亲支持下,焦虑症与 AUDs 发病风险降低相关(风险比 [HR]=0.74,95% 置信区间 [CI]=0.55 - 1.00)。然而,这种效应在 20 岁之前发病的 AUDs 中更为显著。在低水平的母亲支持下,焦虑症与 AUDs 发病风险增加相关(HR = 1.65,95% CI = 1.21 - 2.26)。这种效应在整个青春期和成年期发病的 AUDs 中均存在。父亲支持与 AUDs 无关,也不与焦虑症相互作用。
针对患有焦虑症的青少年的母亲支持开展预防和干预工作可能很有价值,因为这可能是一个对 AUDs 发展进程有重大影响的因素。