镰状细胞病的神经影像学表现。
Neuroimaging findings in sickle cell disease.
作者信息
Thust S C, Burke C, Siddiqui A
机构信息
1 St Thomas Hospital, Guy's and St Thomas' Hospitals NHS Foundation Trust, Radiology Department, London, UK.
出版信息
Br J Radiol. 2014 Aug;87(1040):20130699. doi: 10.1259/bjr.20130699. Epub 2014 May 21.
Abstract
At least 25% of individuals with sickle cell disease will have a neurological complication over their lifetime, often as early as in childhood. Neuroradiological findings in patients with sickle cell disease are common and include acute territorial infarction, silent ischaemia and intracranial haemorrhage. Imaging abnormalities are typically, but not always, manifestations of the underlying vasculopathy. Coexisting acute and chronic pathology may pose challenges to interpretation.
摘要
至少25%的镰状细胞病患者在其一生中会出现神经并发症，通常早在儿童期就会出现。镰状细胞病患者的神经放射学表现很常见，包括急性局部梗死、无症状性缺血和颅内出血。影像学异常通常（但并非总是）是潜在血管病变的表现。急性和慢性病变共存可能给诊断带来挑战。
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