Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada.
Department of Otolaryngology, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada.
JAMA Otolaryngol Head Neck Surg. 2014 Jul;140(7):616-23. doi: 10.1001/jamaoto.2014.778.
Evaluation of pediatric obstructive sleep apnea in resource-limited health care systems necessitates testing modalities that are accurate and more cost-effective than polysomnography.
To trace the clinical pathway of children referred to our sleep laboratory for possible obstructive sleep apnea who were evaluated using nocturnal pulse oximetry and the McGill Oximetry Score.
DESIGN, SETTING, AND PARTICIPANTS: This was a retrospective cohort study of children 2 to 17 years old with suspected obstructive sleep apnea due to adenotonsillar hypertrophy, conducted at a Canadian pediatric tertiary care center.
Nocturnal pulse oximetry studies scored using the McGill Oximetry Score.
For children who underwent adenotonsillectomy we determined the length of time from oximetry to surgery, postoperative length of stay, postoperative readmissions, and emergency department visits in the month following surgery and major surgical complications. We analyzed these outcomes by oximetry result. We compared the cost savings of our diagnostic approach with those of other diagnostic models.
Among 362 children, the median age was 4.8 years (interquartile range, 3.3-6.7), and 61% were male. Two-hundred-sixty-six (73%) and 96 (27%), respectively, had inconclusive and abnormal oximetry results. Eighty of 96 of children with abnormal oximetry results (83%) and 81 of 266 children with inconclusive oximetry results (30%) underwent adenotonsillectomy. Thirty-three of 266 children (12%) underwent further evaluation with polysomnography; of 14 diagnosed as having OSA, 12 underwent adenotonsillectomy. Children with abnormal oximetry results were operated on soonest after testing and triaged based on oximetry results. No child with an inconclusive oximetry result required hospitalization for more than 1 night postoperatively; 14% of children (11 of 80) with an abnormal oximetry result required hospitalization for 2 or 3 nights (χ2 = 12.0; P = .001). Rates of readmissions and emergency department visits were low, irrespective of oximetry results (whether inconclusive or abnormal). We show that our oximetry-based diagnostic approach results in considerable cost savings compared with a polysomnography-for-all approach.
Oximetry studies evaluated with the McGill Oximetry Score expedite diagnosis and treatment of children with adenotonsillar hypertrophy referred for suspected sleep-disordered breathing. When resources for testing for sleep-disordered breathing are rationed or severely limited, our proposed diagnostic approach can help maximize cost-savings and allows sleep laboratories to focus resources on medically complex children requiring polysomnographic evaluation of suspected sleep disorders.
在资源有限的医疗保健系统中评估儿科阻塞性睡眠呼吸暂停需要使用比多导睡眠图更准确和更具成本效益的检测方式。
追踪因腺样体扁桃体肥大而被转至我们睡眠实验室进行可能的阻塞性睡眠呼吸暂停评估的儿童的临床路径,这些儿童使用夜间脉搏血氧测定法和麦吉尔血氧评分进行评估。
设计、地点和参与者:这是一项在加拿大儿科三级保健中心进行的回顾性队列研究,纳入了因腺样体扁桃体肥大而疑似阻塞性睡眠呼吸暂停的 2 至 17 岁儿童。
使用麦吉尔血氧评分对夜间脉搏血氧测定法研究进行评分。
对于接受腺样体扁桃体切除术的儿童,我们确定了从血氧测定到手术的时间、术后住院时间、术后再入院率以及术后一个月内的急诊就诊率和主要手术并发症。我们根据血氧测定结果分析了这些结果。我们比较了我们诊断方法的成本节约与其他诊断模型的成本节约。
在 362 名儿童中,中位年龄为 4.8 岁(四分位距,3.3-6.7),61%为男性。分别有 266(73%)和 96(27%)名儿童的血氧测定结果不确定和异常。80 名血氧测定结果异常的儿童(83%)和 266 名血氧测定结果不确定的儿童(30%)中分别有 81 名和 80 名接受了腺样体扁桃体切除术。266 名儿童中有 33 名(12%)接受了进一步的多导睡眠图评估;14 名被诊断为阻塞性睡眠呼吸暂停的儿童中,有 12 名接受了腺样体扁桃体切除术。血氧测定结果异常的儿童在检测后最快接受手术,并根据血氧测定结果进行分诊。没有血氧测定结果不确定的儿童需要住院超过 1 晚;14%(11/80)血氧测定结果异常的儿童需要住院 2 或 3 晚(χ2=12.0;P=.001)。无论血氧测定结果如何(不确定或异常),再入院率和急诊就诊率均较低。我们表明,与所有儿童都进行多导睡眠图检查的方法相比,我们基于血氧测定的诊断方法可显著节约成本。
使用麦吉尔血氧评分评估的血氧测定研究可加速因腺样体扁桃体肥大而被转至睡眠呼吸障碍疑似儿童的诊断和治疗。当用于睡眠呼吸障碍检测的资源受到限制或严重受限时,我们提出的诊断方法可以帮助最大程度地节约成本,并使睡眠实验室能够将资源集中用于需要多导睡眠图评估疑似睡眠障碍的医学复杂儿童。