Department of Dermatology and Venereology, Karl Landsteiner University of Health Sciences, St. Pölten, Austria; Karl Landsteiner Institute of Dermatological Research, St. Pölten, Austria.
Br J Dermatol. 2014 Dec;171(6):1415-21. doi: 10.1111/bjd.13132. Epub 2014 Nov 19.
Actinic keratoses (AKs) are common precursors of squamous cell carcinomas (SCCs) of the skin making them an important public health issue with information on their prevalence widely lacking.
To define the prevalence of AK in dermatology outpatients in Austria and to identify more accurately the target population for AK screening, treatment and prevention.
Each of the 48 randomly selected Austrian office-based dermatologists simultaneously screened 100 consecutive patients (aged ≥ 30 years) for the presence of AK.
In total, 4449 evaluable patients showed an overall AK prevalence of 31·0%, which was higher in men (39·2%) than in women (24·3%) and increased with age in both sexes. AK distribution among sun-exposed body sites and extent of disease varied with sex and region.
In Austria, AKs are common among dermatology outpatients, who have access to professional education and treatment. Investigations regarding the efficacy of routine AK screening in dermatology outpatients for the prevention of invasive SCC is warranted.
光化性角化病（AK）是皮肤鳞状细胞癌（SCC）的常见前体，因此成为一个重要的公共卫生问题，但有关其患病率的信息却广泛缺乏。
明确奥地利皮肤科门诊患者 AK 的患病率，并更准确地确定 AK 筛查、治疗和预防的目标人群。
48 名随机选择的奥地利皮肤科门诊医生同时对 100 例连续就诊患者（年龄≥30 岁）进行 AK 筛查。
共评估了 4449 例患者，总体 AK 患病率为 31.0%，男性（39.2%）高于女性（24.3%），且在两性中均随年龄增长而增加。AK 在暴露于阳光的身体部位的分布和疾病严重程度因性别和地区而异。
在奥地利，皮肤科门诊患者 AK 较为常见，且患者能够获得专业教育和治疗。有必要对皮肤科门诊患者中常规 AK 筛查预防侵袭性 SCC 的效果进行研究。
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