强迫症药物治疗的未来可能在于更好地理解其异质性。

The future of pharmacotherapy for obsessive-compulsive disorder may lie in a better understanding of its heterogeneity.

作者信息

Brakoulias Vlasios

机构信息

The University of Sydney, Nepean Hospital, Sydney Medical School, Discipline of Psychiatry , PO Box 63, Sydney/Penrith, New South Wales 2751 , Australia +61 2 4734 2585 ; +61 2 4734 3343 ;

出版信息

Expert Opin Pharmacother. 2014 Jul;15(10):1321-3. doi: 10.1517/14656566.2014.924506. Epub 2014 May 28.

DOI:10.1517/14656566.2014.924506

PMID:24866422

Abstract

Pharmacological treatments currently available to treat obsessive-compulsive disorder (OCD) rarely produce remission. This Editorial aims to encourage more targeted research based on the specific OCD symptoms patients primarily present with. Specific OCD symptoms have been associated with distinct clinical characteristics, aetiological hypotheses and treatment responses. Treatment studies should use these findings to develop more targeted pharmacotherapy for patients with OCD.

摘要

目前可用于治疗强迫症（OCD）的药物治疗很少能实现症状缓解。本社论旨在鼓励开展更多基于患者主要呈现的特定强迫症症状的针对性研究。特定的强迫症症状与不同的临床特征、病因假说及治疗反应相关。治疗研究应利用这些发现为强迫症患者开发更具针对性的药物治疗方法。