Povlsen Bo, Shields Adrian M, Bhabra Gev S
Department of Orthopaedic Surgery, Guy's & St. Thomas' Hospital NHS Trust, London, SE1 9RT, UK.
Hand Surg. 2014;19(2):205-9. doi: 10.1142/S021881041450021X.
The gold standard treatment for Dupuytren's contracture is surgical excision of the cord. A non-surgical treatment with collagenase clostridium histolyticum injection is available but appears costly.
To provide data on resource consumption related to surgical and non-surgical treatment for Dupuytren's contracture.
Twenty patients with a single digit Dupuytren's contracture, 10 treated with surgical excision, and 10 treated with a single injection of collagenase.
Minutes spent in theatre, number of follow-up appointments, time to skin healing, and patients return to normal activities of daily living.
The injection group was significantly better regarding theatre time (p < 0.0001), follow-up appointments (p = 0.048), skin healing time (p < 0.001), and return to normal activities of daily living (p = 0.02) than the operated group.
There are significant personal and health economic differences between the two methods of treatment which may influence local choice.
掌腱膜挛缩症的金标准治疗方法是手术切除条索。有一种使用溶组织梭菌胶原酶注射的非手术治疗方法，但成本似乎较高。
提供与掌腱膜挛缩症手术和非手术治疗相关的资源消耗数据。
20例单指掌腱膜挛缩症患者，10例接受手术切除治疗，10例接受单次胶原酶注射治疗。
手术时长、随访预约次数、皮肤愈合时间以及患者恢复正常日常生活的时间。
在手术时长（p < 0.0001）、随访预约次数（p = 0.048）、皮肤愈合时间（p < 0.001）以及恢复正常日常生活时间（p = 0.02）方面，注射组显著优于手术组。
两种治疗方法在个人和健康经济方面存在显著差异，这可能会影响当地的治疗选择。
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