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原发性巨大肝神经内分泌癌:病例报告。

Primary giant hepatic neuroendocrine carcinoma: a case report.

机构信息

Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.

Hepatobiliary Surgery and Liver Transplant Center, A. Cardarelli Hospital, Naples, Italy.

出版信息

Int J Surg. 2014;12 Suppl 1:S218-21. doi: 10.1016/j.ijsu.2014.05.056. Epub 2014 May 29.

Abstract

Carcinoid tumours arise from neuroendocrine cells and may develop in almost any organ. These type of tumours actually are correctly termed neuroendocrine tumours. Hepatic neuroendocrine carcinomas rarely arise as primary tumour; in fact on 100 cases reported in literature just a few of these are of primary nature. We report the case of a giant hepatic neuroendocrine carcinoma in a 55-year-old man. The symptoms were only recurrent hypoglycemia and an abdominal mass. Diagnosis was performed by blood analysis, ultrasonography, TC scan and In111-DTPA-octreotide scan. Surgical treatment occurred by an en bloc removal of the mass and a wide resection with free margins. Histological examination confirmed diagnosis. Clinical and instrumental diagnostic follow-up show the patient still alive, in very good conditions and disease free two years after surgery.

摘要

类癌肿瘤起源于神经内分泌细胞,几乎可以在任何器官中发展。实际上,这类肿瘤被正确地称为神经内分泌肿瘤。肝神经内分泌癌很少作为原发性肿瘤发生;实际上,在文献中报道的 100 例病例中,只有少数是原发性的。我们报告了一例 55 岁男性的巨大肝神经内分泌癌病例。症状仅为反复发作性低血糖和腹部肿块。通过血液分析、超声、CT 扫描和 In111-DTPA-奥曲肽扫描进行诊断。手术治疗采用整块切除肿块和广泛切除,边缘无肿瘤。组织学检查证实了诊断。临床和仪器诊断随访显示,患者在手术后两年仍然存活,状况良好,无疾病。

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