布莱根头皮甲襞掌跖脓疱型银屑病综合指数(B-SNIPI):一种用于测量所有非斑块状银屑病亚型的新型指数。
The Brigham Scalp Nail Inverse Palmoplantar Psoriasis Composite Index (B-SNIPI): a novel index to measure all non-plaque psoriasis subsets.
作者信息
Patel Mital, Liu Stephanie W, Qureshi Abrar, Merola Joseph F
机构信息
From the Department of Dermatology and Department of Medicine, Division of Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.M. Patel, MD; S.W. Liu, MD; A. Qureshi, MD, MPH; J.F. Merola, MD, MMSc.
出版信息
J Rheumatol. 2014 Jun;41(6):1230-2. doi: 10.3899/jrheum.140177.
Psoriasis is a chronic inflammatory disease that encompasses a large spectrum of clinically distinct subtypes. Although chronic plaque psoriasis is reported as the most common form of psoriatic skin disease, there is growing evidence that other variants including scalp, nail, inverse, and palmoplantar psoriasis are prevalent, undertreated, and associated with significant impairment in quality of life. Currently, the Psoriasis Area and Severity Index (PASI) is the standard to assess psoriasis severity as well as response to treatment; however, the PASI has several limitations. In response to this need and as a complementary objective measure to the PASI, we created the Brigham Scalp Nail Inverse Palmoplantar Psoriasis Composite Index (B-SNIPI), based on patient-surveyed, patient-reported outcomes equally weighted with physician assessment of disease activity. Herein we summarize the B-SNIPI as presented at the 2013 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA).
银屑病是一种慢性炎症性疾病,涵盖了一系列临床上不同的亚型。尽管慢性斑块状银屑病被报道为银屑病性皮肤病最常见的形式,但越来越多的证据表明,包括头皮、指甲、反向性和掌跖部银屑病在内的其他变体很普遍,治疗不足,且与生活质量的显著受损相关。目前,银屑病面积和严重程度指数(PASI)是评估银屑病严重程度以及治疗反应的标准;然而,PASI有几个局限性。为满足这一需求,并作为PASI的补充客观指标,我们基于患者调查、患者报告的结果与医生对疾病活动的评估同等加权,创建了布莱根头皮指甲反向掌跖银屑病综合指数(B-SNIPI)。在此,我们总结了在2013年银屑病和银屑病关节炎研究与评估小组(GRAPPA)年会上展示的B-SNIPI。