GRAPPA 2013年会，风湿病学最新进展：银屑病关节炎（PsA）生物标志物项目、毁形性关节炎、PsA-外周型脊柱关节炎流行病学项目。

GRAPPA 2013 Annual Meeting, rheumatology updates: psoriatic arthritis (PsA) biomarker project, arthritis mutilans, PsA-peripheral spondyloarthritis epidemiology project.

作者信息

FitzGerald Oliver, Mease Philip J, Helliwell Philip S, Chandran Vinod

机构信息

From the Department of Rheumatology, St. Vincent's University Hospital and Conway Institute for Biomolecular Research, University College, Dublin, Ireland; Rheumatology Research, Swedish Medical Center, University of Washington School of Medicine, Seattle, Washington, USA; Academic Unit of Musculoskeletal Disease, Chapel Allerton Hospital, Leeds, UK; Division of Rheumatology, Department of Medicine, University of Toronto; Centre for Prognostic Studies in the Rheumatic Diseases, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.O. FitzGerald, MD, Department of Rheumatology, St. Vincent's University Hospital and Conway Institute for Biomolecular Research, University College; P.J. Mease, MD, Rheumatology Research, Swedish Medical Center and Clinical Professor, University of Washington School of Medicine; P.S. Helliwell, DM, PhD, Academic Unit of Musculoskeletal Disease, Chapel Allerton Hospital; V. Chandran, MBBS, MD, DM, PhD, Division of Rheumatology, Department of Medicine, University of Toronto, and Centre for Prognostic Studies in the Rheumatic Diseases, Toronto Western Hospital, University Health Network.

出版信息

J Rheumatol. 2014 Jun;41(6):1244-8. doi: 10.3899/jrheum.140181.

DOI:10.3899/jrheum.140181

PMID:24882863

Abstract

At the 2013 annual meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), several key GRAPPA projects on musculoskeletal aspects of psoriatic disease were reviewed. In this article, lead investigators summarize the progress made in a multicenter study, the PsA BioDam (Psoriatic Arthritis Biomarkers for Joint Damage), to identify soluble biomarkers for joint damage, as well as developing classification criteria for arthritis mutilans. Also reviewed are concepts and rationale behind a proposal to study classification criteria for peripheral spondyloarthritis, including PsA, reactive arthritis, inflammatory bowel disease-associated arthritis, and undifferentiated arthritis.

摘要

在2013年银屑病和银屑病关节炎研究与评估小组（GRAPPA）年会上，回顾了GRAPPA几个关于银屑病性疾病肌肉骨骼方面的关键项目。在本文中，主要研究者总结了一项多中心研究——银屑病关节炎关节损伤生物标志物（PsA BioDam）——在识别关节损伤可溶性生物标志物以及制定毁形性关节炎分类标准方面取得的进展。还回顾了一项关于研究外周型脊柱关节炎（包括银屑病关节炎、反应性关节炎、炎症性肠病相关性关节炎和未分化关节炎）分类标准的提议背后的概念和基本原理。