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大量腹水情况下的姑息性胃造口术。

Palliative gastrostomy in the setting of voluminous ascites.

作者信息

O'Connor Owen J, Diver Elizabeth, McDermott Shaunagh, Covarrubias Diego A, Shelly Martin J, Growdon Whitfield, Hahn Peter F, Mueller Peter R

机构信息

1 Department of Radiology, Massachusetts General Hospital , Boston, Massachusetts.

出版信息

J Palliat Med. 2014 Jul;17(7):811-21. doi: 10.1089/jpm.2013.0397. Epub 2014 Jun 2.

Abstract

OBJECTIVE

We report the indications, methods, and complications of percutaneous gastrostomy/gastrojejunostomy (G/GJ) in patients with voluminous ascites.

METHODS

Following institutional review board approval, 69 patients (14 male, 55 female, mean age 58±12 years, range 32-89 years) who underwent percutaneous G/GJ with paracentesis were identified from a prospectively acquired database. Electronic medical record data extracted included diagnosis, method of G/GJ insertion, clinical course, and complications, which were graded by The Society of Interventional Radiology (SIR) criteria. Statistics were performed using Graphpad Instat.

RESULTS

Sixty-six G and three GJ catheters were placed in 62 patients with malignant and 7 patients with benign disease; 47 procedures were conducted using fluoroscopy and 22 using computed tomography (CT; 10 patients had failed fluoroscopy). Sixty-six patients had 1980±1371 mL (range, 20-5000 mL) ascites drained (more in males, p=0.01) 0.8±1.6 days (range, 0-5 days) prior to placement. Forty-one patients had significantly less ascites (1895±1426 mL; range, 100-5400 mL) drained after G/GJ (p>0.0.5). Mean survival after insertion was 43±57 days (range, 1-252 days) among 38 patients for whom data were available. Fifty-six patients had a mean postprocedure hospital stay of 8.6±8.4 days (range, 0-45 days); 3 were outpatients and 10 patients died in the hospital. Successful gastropexy was confirmed on subsequent cross-sectional imaging in 22 of 25 patients. There were 25 tube maintenance issues that included catheter displacement and leakage, one patient experienced hemorrhage, and there were two deaths. All except one patient had satisfactory gastrostomy function.

CONCLUSION

Effective G/GJ placement is possible in most patients with voluminous ascites provided ascites is drained and gastrocutaneous fistula formation occurs. Caution is advised; placement is generally for fragile terminal patients, and fluoroscopy or CT guidance is required.

摘要

目的

我们报告大量腹水患者经皮胃造口术/胃空肠造口术(G/GJ)的适应证、方法及并发症。

方法

经机构审查委员会批准,从一个前瞻性获取的数据库中识别出69例行经皮G/GJ联合腹腔穿刺术的患者(14例男性,55例女性,平均年龄58±12岁,范围32 - 89岁)。提取的电子病历数据包括诊断、G/GJ置入方法、临床病程及并发症,并根据介入放射学会(SIR)标准进行分级。使用Graphpad Instat进行统计分析。

结果

62例恶性疾病患者和7例良性疾病患者置入了66根胃造口管和3根胃空肠造口管;47例操作使用了荧光透视,22例使用了计算机断层扫描(CT;10例患者荧光透视失败)。66例患者在置入前0.8±1.6天(范围0 - 5天)引流出1980±1371 mL(范围20 - 5000 mL)腹水(男性引流量更多,p = 0.01)。41例患者在G/GJ术后引流出的腹水明显减少(1895±1426 mL;范围100 - 5400 mL)(p>0.05)。在有数据的38例患者中,置入后的平均生存期为43±57天(范围1 - 252天)。56例患者术后平均住院时间为8.6±8.4天(范围0 - 45天);3例为门诊患者,10例患者在医院死亡。25例患者中有22例在后续的横断面成像中证实胃固定成功。有25个管道维护问题,包括导管移位和渗漏,1例患者发生出血,2例死亡。除1例患者外,所有患者的胃造口功能均令人满意。

结论

对于大多数大量腹水患者,只要引流出腹水并形成胃皮肤瘘,有效置入G/GJ是可行的。建议谨慎操作;一般适用于病情危重的终末期患者,且需要荧光透视或CT引导。

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