采用嗜酸性-5'-马来酰亚胺结合试验诊断遗传性球形红细胞增多症。

Hereditary spherocytosis diagnosed with the eosin-5'-maleimide binding test.

作者信息

Watanabe Toru, Ono Hiroyuki, Tajima Iwao, Ishigaki Hidetoshi, Hakamata Akio, Shirai Masami, Endoh Akira, Hongo Teruaki

机构信息

Department of Pediatrics, Iwata City Hospital, Iwata, Japan.

出版信息

Pediatr Int. 2014 Jun;56(3):427-9. doi: 10.1111/ped.12293.

DOI:10.1111/ped.12293

PMID:24894931

Abstract

We describe three cases of hereditary spherocytosis (HS) diagnosed using the eosin-5'-maleimide (EMA) binding test and discuss the relevance of the EMA binding test. In Japan, this test is not widely used because the prevalence of HS is low. This test is a valuable screening test for the diagnosis of HS.

摘要

我们描述了三例使用5'-马来酰亚胺基曙红（EMA）结合试验诊断的遗传性球形红细胞增多症（HS）病例，并讨论了EMA结合试验的相关性。在日本，由于HS的患病率较低，该试验未得到广泛应用。该试验是诊断HS的一项有价值的筛查试验。