Nedved D, Connor C, Sharma P, O'Neil M
Pathologica. 2014 Mar;106(1):16-21.
We report a case of a 71-year-old female with a palpable breast mass. Pathologic evaluation of the breast mass showed a unique collision tumour with a high-grade invasive and in-situ ductal carcinoma component and a high-grade neuroendocrine carcinoma component. The neuroendocrine component turned out to be Merkel cell carcinoma (MCC), with immunohistochemical confirmation. To the best of our knowledge, this is the first case report of a collision tumour with ordinary ductal carcinoma and MCC in the breast.
我们报告一例71岁女性,其乳房可触及肿块。乳房肿块的病理评估显示为一种独特的碰撞瘤,具有高级别浸润性和原位导管癌成分以及高级别神经内分泌癌成分。经免疫组化证实,神经内分泌成分原来是默克尔细胞癌(MCC)。据我们所知,这是首例关于乳房中普通导管癌与MCC碰撞瘤的病例报告。