Mahdavi Omid, Boostani Najmehalsadat, Karimi Sharareh, Tabesh Adel
Assistant Professor, Department of Oral and Maxillofacial Medicine, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Resident, Department of Anesthesiology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
J Dent (Tehran). 2013 Nov;10(6):562-8. Epub 2013 Nov 30.
Sinonasal undifferentiated carcinoma is an extremely rare malignancy of the paranasal sinuses and nasal cavity. It is of unknown etiology, and occurs more commonly in the elderly men, with a routinely shown aggressive behavior and poor prognosis for survival. Radiographically, it looks like severe osteomyelitis. Histopathologic study is essential to confirm diagnosis, and the undifferentiated histologic appearance often necessitates immunohistochemical studies for differentiation from other high-grade neoplasms. We present an 83-year-old man complaining of pain and unilateral swelling on the left side of the face due to a rare malignant tumor of maxillary sinus origin, a sinonasal undifferentiated carcinoma. He underwent hemimaxillectomy and radiotherapy, but refused chemotherapy. Maxillary sinus malignancy may be presented with unspecific symptoms mimicking sinusitis or dental pain. Coming across such symptoms, the physician or dentist must consider malignancies as well, and carry out medical and dental workups.
鼻窦未分化癌是一种极其罕见的鼻窦和鼻腔恶性肿瘤。其病因不明,更常见于老年男性,通常表现出侵袭性生长行为,生存预后较差。在影像学上,它看起来像严重的骨髓炎。组织病理学研究对于确诊至关重要,未分化的组织学表现常常需要进行免疫组化研究以与其他高级别肿瘤相鉴别。我们报告一名83岁男性,因起源于上颌窦的罕见恶性肿瘤——鼻窦未分化癌,出现左侧面部疼痛和单侧肿胀。他接受了半侧上颌骨切除术和放疗,但拒绝化疗。上颌窦恶性肿瘤可能表现为类似鼻窦炎或牙痛的非特异性症状。遇到此类症状时,医生或牙医也必须考虑到恶性肿瘤的可能,并进行医学和牙科检查。