Sardana Nitin, Wallace Dustin, Agrawal Radheshyam, Aoun Elie
Division of Gastroenterology, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.
BMJ Case Rep. 2014 Jun 10;2014:bcr2014204677. doi: 10.1136/bcr-2014-204677.
An 89-year-old man with a history of coronary artery disease status post coronary artery bypass grafting and atrial fibrillation on aspirin and warfarin, presented to the emergency department with a symptom of haemoptysis. He reported a history of dysphagia for 3 months prior to presentation, but had yet to seek medical attention. On presentation, he was hypotensive and tachycardic with a haemoglobin of 6.6 g/dL and an International Normalised Ratio (INR) of 3.9. Esophagogastroduodenoscopy was performed and showed active bleeding from Zenker's diverticulum. The patient's INR was reversed with fresh frozen plasma and his anaemia was treated with packed red blood cells. The bleeding stopped after reversal of his INR. A barium swallow confirmed a 9 cm Zenker's diverticulum. The patient had a diverticulectomy and cricopharyngeal myotomy. Histology showed mild chronic inflammation of the mucosa, but no ulceration. The patient was discharged without any further bleeding episodes.
一名89岁男性,有冠状动脉疾病史,曾行冠状动脉搭桥术,因心房颤动服用阿司匹林和华法林,因咯血症状就诊于急诊科。他报告在就诊前3个月有吞咽困难史,但尚未就医。就诊时,他血压低、心动过速,血红蛋白为6.6 g/dL,国际标准化比值(INR)为3.9。进行了食管胃十二指肠镜检查,显示Zenker憩室有活动性出血。患者的INR通过新鲜冰冻血浆纠正,贫血通过浓缩红细胞治疗。INR纠正后出血停止。钡餐检查证实有一个9厘米的Zenker憩室。患者接受了憩室切除术和环咽肌切开术。组织学显示黏膜有轻度慢性炎症,但无溃疡。患者出院,未再发生出血事件。