Jarade Elias F, Dirani Ali, Jabbour Elyse, Antoun Joelle, Tomey Karim F
Beirut Eye Specialist Hospital, Beirut, Lebanon ; Mediclinic Dubai Mall, Dubai, United Arab Emirates.
Hotel Dieu de France Hospital, Saint Joseph University, Beirut, Lebanon.
Clin Ophthalmol. 2014 May 27;8:1047-50. doi: 10.2147/OPTH.S62096. eCollection 2014.
Malignant glaucoma, or aqueous misdirection syndrome, is a condition characterized by sudden intraocular pressure (IOP) elevation, and it is usually unilateral and induced by ocular surgical intervention or by medical therapy. Here, we report a case of simultaneous bilateral malignant glaucoma in a young patient with no history of any ocular diseases.
A case of a 24-year-old female with no apparent previous history of ocular medical or surgical conditions was referred to our hospital because of recent bilateral IOP elevation associated with a severe drop in vision and shallow anterior chamber with no posterior segment anomalies detected by ocular ultrasound in both eyes. Yttrium aluminum garnet (YAG) laser iridotomy dropped the IOP only temporarily and the patient received topical atropine treatment with combined trabeculectomy and anterior vitrectomy.
In this case, the patient had a typical presentation of bilateral malignant glaucoma and her IOP dropped only temporarily following laser iridotomy to rise again shortly thereafter. Also, deepening of the anterior chamber and IOP decrease after topical atropine was very supportive of the diagnosis of malignant glaucoma. Successful management with trabeculectomy and limited vitrectomy also affirmed the diagnosis of malignant glaucoma.
This is a very rare case of bilateral malignant glaucoma in a young adult without any prior eye conditions; only one similar case has been reported in the literature. We propose our own theory regarding this simultaneous occurrence of the pathology based on previously published studies about the presence of communication between the two eyes along the cerebrospinal fluid pathways.
恶性青光眼,即房水错流综合征,是一种以眼压(IOP)突然升高为特征的疾病,通常为单侧,由眼科手术干预或药物治疗诱发。在此,我们报告一例年轻患者同时发生双侧恶性青光眼,该患者无任何眼部疾病史。
一名24岁女性,既往无明显眼部疾病或手术史,因近期双侧眼压升高、视力严重下降以及前房变浅而被转诊至我院,双眼眼部超声未发现后段异常。钇铝石榴石(YAG)激光虹膜切开术仅使眼压暂时下降,患者接受了局部阿托品治疗,并联合小梁切除术和前部玻璃体切除术。
在该病例中,患者表现为典型的双侧恶性青光眼,激光虹膜切开术后眼压仅暂时下降,随后不久又再次升高。此外,局部使用阿托品后前房加深和眼压降低,这非常支持恶性青光眼的诊断。小梁切除术和有限玻璃体切除术的成功治疗也证实了恶性青光眼的诊断。
这是一例非常罕见的年轻成年人双侧恶性青光眼病例,且患者之前无任何眼部疾病;文献中仅报道过一例类似病例。我们基于先前发表的关于双眼沿脑脊液途径存在连通性的研究,提出了关于这种病理情况同时发生的我们自己的理论。