Faverani Leonardo Perez, Ferreira Sabrina, Ferreira Gabriel Ramalho, Coléte Juliana Zorzi, Aranega Alessandra Marcondes, Garcia Júnior Idelmo Rangel
From the Division of Oral and Maxillofacial Surgery, Department of Surgery and Integrated Clinic, Aracatuba Dental School, Univ Estadual Paulista - Julio de Mesquita Filho - UNESP, Araçatuba, Brazil.
J Craniofac Surg. 2014 Jul;25(4):e344-6. doi: 10.1097/SCS.0000000000000750.
Central giant cell granuloma (CGCG) is an intraosseous lesion consisting of fibrous cellular tissue that contains multiple foci of hemorrhage, multinucleated giant cells, and occasional trabeculae of woven bone. An 8-year-old boy presented himself complaining of a painless swelling in the left maxilla that had started 1 year. Computed tomography (CT) scan confirmed a poorly defined multilocular radiolucent lesion in the left maxilla crossing the midline. The patient underwent enucleation through an intraoral approach of the lesion. The biopsy revealed multinucleated giant cells in a fibrous stroma. A CT was taken approximately 1 year postoperatively. There was no clinical or radiographic evidence of recurrence. Therefore, surgical treatment of CGCG can be performed, trying to preserve the surrounding anatomic structures, which can be maintained in case the lesion does not show an aggressive clinical behavior, avoiding large surgical defects which are undesirable in children.
中央巨细胞肉芽肿（CGCG）是一种骨内病变，由纤维细胞组织构成，其中含有多个出血灶、多核巨细胞以及偶尔出现的编织骨小梁。一名8岁男孩前来就诊，主诉左上颌无痛性肿胀，已持续1年。计算机断层扫描（CT）显示左上颌有一个边界不清的多房性透射性病变，跨越中线。患者通过经口入路对病变进行了摘除术。活检显示纤维基质中有多核巨细胞。术后约1年进行了CT检查。没有临床或影像学复发证据。因此，对于CGCG可进行手术治疗，尽量保留周围解剖结构，若病变未表现出侵袭性临床行为则可维持这些结构，避免出现儿童不宜有的大的手术缺损。
