1 Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA.
AJR Am J Roentgenol. 2014 Jul;203(1):196-200. doi: 10.2214/AJR.13.11346.
The objective of our study was to help clarify the role of CT-guided pudendal nerve blocks in the problematic and poorly understood entity of pudendal neuralgia (PN).
Over a 1-year period, 52 CT-guided pudendal nerve blocks were performed in 31 patients (28 women, three men; age range, 22-80 years) who suffered from chronic pelvic pain with a presumed diagnosis of PN. A combination of anesthetic and steroid was injected into the pudendal (Alcock) canal. Pre- and postprocedural pain scores (0-10) were tallied and assessed by Student t tests. A p value < 0.05 was indicative of a significant difference.
All procedures were successful technically, which was defined as contrast material filling the pudendal canal on CT and subsequent infusion of anesthetic and steroid. Pre- and postprocedural pain scores ranged from 2 to 10 (mean score, 6.13) and 0-10 (mean score, 2.14), respectively; the difference was statistically significant for each nerve block session (first session, p < 0.001; second session, p < 0.001; third session, p = 0.049). Of the 31 patients, two had long-term relief with pudendal nerve blocks alone. Fourteen had subsequent surgery based on initial improvement with block(s), and all 14 patients improved with surgical nerve release. Two patients had no diagnostic response and the diagnosis of PN was excluded. The gynecologic service followed the remaining 13 patients clinically.
CT-guided pudendal nerve blocks appear to be valuable diagnostically for PN and uncommonly therapeutically. On the basis of these preliminary results, we have developed an algorithm for the role of the procedure for PN.
本研究旨在阐明 CT 引导阴部神经阻滞在阴部神经痛(PN)这一复杂且尚未完全明确的疾病中的作用。
在为期 1 年的时间内,对 31 名患有慢性盆腔疼痛且疑似患有 PN 的患者(28 名女性,3 名男性;年龄 22-80 岁)实施了 52 次 CT 引导阴部神经阻滞。将麻醉剂和类固醇混合液注射到阴部(Alcock)管内。通过学生 t 检验对术前和术后的疼痛评分(0-10 分)进行了统计和评估。p 值<0.05 表示差异有统计学意义。
所有操作均在技术上获得成功,定义为 CT 显示阴部管内有对比剂填充,随后注入麻醉剂和类固醇。术前和术后疼痛评分分别为 2-10 分(平均评分 6.13 分)和 0-10 分(平均评分 2.14 分),每个神经阻滞治疗均有显著差异(第一次治疗,p<0.001;第二次治疗,p<0.001;第三次治疗,p=0.049)。31 名患者中,有 2 名患者仅通过阴部神经阻滞获得了长期缓解。14 名患者因阻滞治疗初始改善而接受了后续手术,所有 14 名患者在接受手术神经松解后均得到改善。2 名患者对诊断性阻滞无反应,排除了 PN 诊断。妇产科服务团队对其余 13 名患者进行了临床随访。
CT 引导阴部神经阻滞在 PN 的诊断中具有一定价值,且很少具有治疗作用。基于这些初步结果,我们为该操作在 PN 中的作用制定了一个应用流程。