Mittal Tarun, Rathi Manish
Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Int J Rheum Dis. 2014 Nov;17(8):834-44. doi: 10.1111/1756-185X.12424. Epub 2014 Jun 21.
Renal involvement is a common occurrence in subjects with rheumatological diseases and can develop either due to the disease itself or secondary to drugs used in the treatment. The prevalence of renal involvement and its severity depends on the underlying disease as well as aggressiveness of the therapy. For most rheumatological diseases, renal involvement heralds a poor prognosis and warrants aggressive immunosuppressive treatment. Thus, it is important to diagnose and manage them at an early stage. On the other hand, patients with primary kidney disease can also develop rheumatological manifestations which need to be differentiated from the former. This article provides the nephrologist's perspective upon various rheumatological disorders and associated renal involvement with the aim of sensitizing the rheumatological community about them, resulting in better management of these subjects.
肾脏受累在患有风湿性疾病的患者中很常见，其发生可能是由于疾病本身，也可能是治疗中使用的药物所致。肾脏受累的患病率及其严重程度取决于基础疾病以及治疗的积极程度。对于大多数风湿性疾病而言，肾脏受累预示着预后不良，需要积极的免疫抑制治疗。因此，早期诊断和处理这些情况很重要。另一方面，原发性肾病患者也可能出现风湿性表现，需要与前者相鉴别。本文从肾脏病学家的角度阐述了各种风湿性疾病及相关的肾脏受累情况，旨在提高风湿学界对这些情况的认识，从而更好地管理这些患者。
