Mavros Michael N, Velmahos George C, Larentzakis Andreas, Yeh Daniel Dante, Fagenholz Peter, de Moya Marc, King David R, Lee Jarone, Kaafarani Haytham M A
Division of Trauma, Emergency Surgery, and Surgical Critical Care, Department of Surgery, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, USA; Department of Surgery, MedStar Washington Hospital Center, Washington, DC 20010, USA.
Division of Trauma, Emergency Surgery, and Surgical Critical Care, Department of Surgery, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, USA.
Am J Surg. 2014 Oct;208(4):626-31. doi: 10.1016/j.amjsurg.2014.02.014. Epub 2014 May 4.
Little evidence exists regarding the characteristics of intraoperative adverse events (iAEs).
Administrative data, the American College of Surgeons - National Surgical Quality Improvement Project, and systematic review of operative reports were used to confirm iAEs in abdominal surgery patients. Standard American College of Surgeons - National Surgical Quality Improvement Project data were supplemented with variables including injury type/organ, phase of operation, adhesions, repair type, and intraoperative consultations.
Two hundred twenty-seven iAEs (187 patients) were confirmed in 9,292 patients. Most common injuries were enterotomies during intestinal surgery (68%) and vessel injuries during hepatopancreaticobiliary surgery (61%); 108 iAEs (48%) specifically occurred during adhesiolysis. A third of the iAEs required organ/tissue resection or complex reconstruction. Because of iAEs, 20 intraoperative consults (11%) were requested and 9 of the 66 (16%) laparoscopic cases were converted to open. Thirty-day mortality and morbidity were 6% and 58%, respectively. The complications included perioperative transfusions (36%), surgical site infection (19%), systemic sepsis (13%), and failure to wean off the ventilator (12%).
iAEs commonly occur in reoperative cases requiring lysis of adhesions and possibly lead to increased patient morbidity. Understanding iAEs is essential to prevent their occurrence and mitigate their adverse effects.
关于术中不良事件(iAEs)的特征,现有证据较少。
利用管理数据、美国外科医师学会-国家外科质量改进项目以及对手术报告的系统回顾,来确认腹部手术患者中的iAEs。美国外科医师学会-国家外科质量改进项目的标准数据补充了包括损伤类型/器官、手术阶段、粘连、修复类型和术中会诊等变量。
在9292例患者中确认了227例iAEs(187例患者)。最常见的损伤是肠道手术中的肠切开术(68%)和肝胰胆手术中的血管损伤(61%);108例iAEs(48%)具体发生在粘连松解术期间。三分之一的iAEs需要进行器官/组织切除或复杂重建。由于iAEs,需要进行20次术中会诊(11%),66例(16%)腹腔镜手术中有9例转为开放手术。30天死亡率和发病率分别为6%和58%。并发症包括围手术期输血(36%)、手术部位感染(19%)、全身性败血症(13%)和脱机失败(12%)。
iAEs常见于需要粘连松解的再次手术病例中,并可能导致患者发病率增加。了解iAEs对于预防其发生和减轻其不良影响至关重要。