Suzuki Tsugutoshi, Nakamura Yoshihide, Yoshida Shuichiro, Yoshida Yoko, Nakamura Kae, Sasaki Takeshi, Fujino Mitsuhiro, Kawasaki Yuki, Ehara Eiji, Murakami Yosuke, Shintaku Haruo
Department of Pediatric Electrophysiology.
Department of Pediatric Electrophysiology.
Heart Rhythm. 2014 Nov;11(11):1948-56. doi: 10.1016/j.hrthm.2014.06.024. Epub 2014 Jun 19.
Idiopathic ventricular tachycardia of left anterior fascicular origin (IVT-LAF) is a rare condition, and radiofrequency catheter ablation (RFCA) therapy has not been reported in children.
This study aimed to evaluate the procedures and outcomes of RFCA for pediatric IVT-LAF.
Pediatric IVT-LAF cases for which RFCA was performed between June 2006 and May 2012 at our hospital were reviewed.
Of 537 pediatric cases of RFCA, 6 had IVT-LAF; 4 had anterior fascicular involvement only, while 2 had both anterior and posterior fascicular involvement. All 6 of them underwent RFCA at the median age of 8.8 years (range 4.3-14.3 years). RFCA was successful in all patients, but 4 had recurrence and underwent 1-3 additional sessions of RFCA. In a total of 10 RFCA sessions, the overall recurrence rate was 50%. The site of RFCA was determined on the basis of detection of diastolic potential during ventricular tachycardia (7 sessions) or isolated delayed potential during sinus rhythm (1) or by pace mapping (2). During the median follow-up period of 33 months, no further recurrence was reported except for 1 patient, who had a recurrence and was scheduled for additional session at the time of this report. Major complications included 1 case of complete atrioventricular block and 1 case of complete left bundle branch block.
Despite a high recurrence rate and a few complications, RFCA of the site of isolated delayed potential or diastolic potential, if applied cautiously, is a possible treatment of choice for pediatric IVT-LAF.
左前分支起源的特发性室性心动过速(IVT-LAF)是一种罕见病症,儿童射频导管消融(RFCA)治疗尚无报道。
本研究旨在评估儿童IVT-LAF的RFCA手术及疗效。
回顾2006年6月至2012年5月在我院接受RFCA治疗的儿童IVT-LAF病例。
537例儿童RFCA病例中,6例为IVT-LAF;4例仅累及前分支,2例同时累及前、后分支。所有6例均在8.8岁(范围4.3 - 14.3岁)接受RFCA治疗。所有患者RFCA均成功,但4例复发,接受了1 - 3次额外的RFCA治疗。总共10次RFCA治疗中,总体复发率为50%。RFCA部位根据室性心动过速时舒张期电位检测(7次)、窦性心律时孤立延迟电位检测(1次)或起搏标测(2次)确定。中位随访期33个月期间,除1例复发且在本报告时计划再次治疗外,未再报告复发情况。主要并发症包括1例完全性房室传导阻滞和1例完全性左束支传导阻滞。
尽管复发率高且有一些并发症,但谨慎应用时,对孤立延迟电位或舒张期电位部位进行RFCA是儿童IVT-LAF可能的治疗选择。