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[克罗恩病肠膀胱瘘的外科治疗]

[Surgical management of entero-vesical fistulas in Crohn's disease].

作者信息

Makni Amin, Saidani Ahmed, Karoui Sami, Chebbi Faouzi, Rebai Wael, Ksantini Rachid, Fteriche Fadhel, Jouini Mohamed, Montassar Kacem, Filali Azza, Ben Safta Zubeir

出版信息

Tunis Med. 2014 Mar;92(3):197-200.

Abstract

BACKGROUND

Crohn's disease (CD) is a chronic inflammatory disease of the intestine that can cause an attack by contiguity of the urinary tract. Although the shape is common and fistulizing 35% of all patients with CD, entero-urinary fistulas are rare and only seen in 2-8% of patients. aim: To report the frequency of occurrence of this complication among the group of surgical forms of CD. Describe the different pathophysiological mechanisms of occurrence of entero-vesical fistula (EVF) during the CD. methods: We report, retrospectively, seven observations of EVF complicating MC made during the period from 01/01/1998 until 31/12/2010. results: The mean age of patients was 30 years. There were 3 men and 4 women. All patients had clinical signs and radiological EVF. In six patients, CD was ileo-caecal and the ileo-vesical fistula was between the last loop and the bladder. In one patient, the CD was located only in colon, and the fistula was between sigmoid colon and bladder. Level of the bladder, it was a false EVF in five patients and a true EVF in two patients. In these last two, the fistula of 2 mm, was on the top of the bladder. Treatment consisted in all cases by a disconnect between the digestive tract and bladder, resection with restoration of digestive continuity, and if the case of true EVF, a freshening the edges of the fistula with suture of the bladder's wall and drainage. The postoperative course was uneventful in six patients and marked by an outbreak intraperitoneal abcess in one patient who had evolved under medical treatment. After a mean of eleven months, no recurrence surgery was noted.

CONCLUSION

Despite advanced treatment in the context of CD, the indication in EVF is a surgical treatment. Surgery helps fight against the consequences of septic urinary tract, but also to launder bowel disease and reduce the risk of recurrence in the short term.

摘要

背景

克罗恩病(CD)是一种肠道慢性炎症性疾病,可导致泌尿系统受到连续性侵袭。虽然瘘管形成在所有CD患者中很常见,占35%,但肠-泌尿瘘很少见,仅见于2%-8%的患者。目的:报告该并发症在CD手术病例组中的发生频率。描述CD期间肠膀胱瘘(EVF)发生的不同病理生理机制。方法:我们回顾性报告了1998年1月1日至2010年12月31日期间发生的7例EVF并发CD的病例。结果:患者的平均年龄为30岁。男性3例,女性4例。所有患者均有临床症状和放射性EVF。6例患者的CD为回盲部型,回肠膀胱瘘位于最后一段肠袢与膀胱之间。1例患者的CD仅位于结肠,瘘管位于乙状结肠与膀胱之间。在膀胱层面,5例为假性EVF,2例为真性EVF。在这2例真性EVF中,瘘管为2mm,位于膀胱顶部。所有病例的治疗均包括消化道与膀胱分离、切除并恢复消化道连续性,对于真性EVF,需修整瘘管边缘并缝合膀胱壁及引流。6例患者术后病程顺利,1例在接受药物治疗过程中出现腹腔脓肿。平均11个月后,未发现手术复发。

结论

尽管在CD的背景下有先进的治疗方法,但EVF的治疗指征仍是手术治疗。手术有助于对抗泌尿系统感染的后果,也有助于清洁肠道疾病并降低短期内复发的风险。

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