Janota Jan, Šebková Sylva, Višňovská Magda, Kudláčková Jana, Hamplová Drahomíra, Zach Jiří
Department of Neonatology, Thomayer Hospital Prague, Prague, Czech Republic; Institute of Pathological Physiology, First Medical Faculty, Charles University in Prague, Prague, Czech Republic.
Acta Paediatr. 2014 Oct;103(10):1053-6. doi: 10.1111/apa.12731. Epub 2014 Jul 29.
To assess the impact of a hand hygiene protocol, using hand washing, alcohol hand rub and gloves when caring for preterm infants born after 31 weeks of gestation, on the incidence of neonatal late onset sepsis (LOS).
All babies delivered between 32 + 0 and 36 + 6 weeks gestation and admitted to the neonatal intensive care unit during a 14-month period were included. We followed a hand hygiene protocol with hand washing and alcohol hand rub (hand rub period) for the first 7 months and a protocol of hand washing, alcohol hand rub and gloves (gloves period) for the second 7 months. The hand rub and gloves groups consisted of 111 and 89 patients, respectively.
Five patients were diagnosed with a total of six episodes of LOS in the hand rub group, and the incidence of LOS during the hand rub period was 2.99/1000 hospital days and 54.1/1000 admissions. There were no patients diagnosed with LOS during the gloves period (significant decrease, p = 0.028).
Using a hand hygiene protocol with hand washing, hand rub and gloves significantly reduced the incidence of LOS in preterm newborns, and the results suggest that it may produce a sustained improvement in the infection rate.
评估在护理孕31周后出生的早产儿过程中，采用洗手、酒精擦手和戴手套的手部卫生方案对新生儿晚发性败血症（LOS）发病率的影响。
纳入孕32 + 0至36 + 6周出生且在14个月期间入住新生儿重症监护病房的所有婴儿。我们在最初7个月遵循洗手和酒精擦手的手部卫生方案（擦手期），在随后7个月遵循洗手、酒精擦手和戴手套的方案（手套期）。擦手组和手套组分别有111例和89例患者。
擦手组有5例患者共发生6次LOS发作，擦手期LOS发病率为每1000个住院日2.99例，每1000例入院患者54.1例。手套期无患者被诊断为LOS（显著下降，p = 0.028）。
采用洗手、擦手和戴手套的手部卫生方案可显著降低早产儿LOS的发病率，结果表明这可能会持续改善感染率。
