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随机对照试验:超声引导下腹横肌平面阻滞用于肾移植。

A randomised controlled trial of ultrasound-guided transversus abdominis plane block for renal transplantation.

机构信息

Warrington and Halton Hospital NHS Foundation Trust, Warrington, UK.

出版信息

Anaesthesia. 2014 Nov;69(11):1222-6. doi: 10.1111/anae.12704. Epub 2014 Jun 28.

DOI:10.1111/anae.12704
PMID:24974901
Abstract

We conducted this study to evaluate the efficacy of a transversus abdominis plane block in reducing morphine requirements in the first 24 h after renal transplant surgery. We performed transversus abdominis plane injections under ultrasound guidance in 54 patients with either 20 ml levobupivacaine 0.5% (n = 27) or 20 ml saline 0.9% (n = 27). All patients received regular paracetamol and patient-controlled analgesia postoperatively. Three participants were not studied owing to protocol violations. In the remaining 51 patients, median (IQR [range]) morphine consumption in the first 24 h was similar in both the transversus abdominis plane group (19.4 (11.7-28.6 [0.5-49.8]) mg) and the control group (16.4 (12.0-31.0 [0.0-61.7]) mg), p = 0.94. We found that use of ultrasound-guided transversus abdominis plane block for renal transplantation did not reduce 24-h morphine requirements.

摘要

我们进行这项研究,旨在评估腹横肌平面阻滞在肾移植手术后 24 小时内减少吗啡需求的效果。我们在 54 名患者中进行了超声引导下的腹横肌平面注射,其中 20ml 左旋布比卡因 0.5%(n=27)或 20ml 生理盐水 0.9%(n=27)。所有患者术后均接受常规扑热息痛和患者自控镇痛。由于违反方案,有 3 名参与者未进行研究。在其余 51 名患者中,腹横肌平面组(19.4(11.7-28.6[0.5-49.8])mg)和对照组(16.4(12.0-31.0[0.0-61.7])mg)在 24 小时内吗啡消耗量中位数(IQR[范围])相似,p=0.94。我们发现,对于肾移植手术,使用超声引导的腹横肌平面阻滞并不能减少 24 小时吗啡需求。

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