Paradisi Roberto, Barzanti Rita, Fabbri Raffaella
Department of Obstetrics and Gynecology and Reproductive Biology, Alma Mater Studiorum University of Bologna, Bologna, Italy.
Curr Opin Obstet Gynecol. 2014 Aug;26(4):295-301. doi: 10.1097/GCO.0000000000000077.
To evaluate the reproductive outcomes and surgical techniques of the hysteroscopic metroplasty in women with septate uterus and recurrent abortions or primary unexplained infertility.
Septate uterus is the most frequent congenital uterine anomaly caused by inadequate resorption of the Müllerian ducts. Hysteroscopic metroplasty has replaced the traditional laparotomy approach because of its positive and satisfactory outcomes in pregnancy and live-birth rates, and also many different postoperative benefits. The aim of metroplasty is to restore a normal anatomy of the uterine cavity as a prerequisite for a positive implantation and subsequent good obstetrical outcomes. This treatment clearly demonstrates its effectiveness both in recurrent abortion and in primary unexplained infertility.
The hysteroscopic metroplasty with its simplicity, safety, and improved reproductive outcomes has liberalized the approach to treatment. Today, hysteroscopic metroplasty is a common practice to treat septate uterus with salutary effects both in infertile patients and in patients with recurrent pregnancy loss or premature labor, especially if in-vitro fertilization is being contemplated. Decisions on when to treat uterine septa are discussed in particular because of lack of prospective, randomized controlled trials.
评估宫腔镜子宫纵隔切除术治疗纵隔子宫合并复发性流产或原发性不明原因不孕症患者的生殖结局及手术技术。
纵隔子宫是最常见的先天性子宫畸形,由苗勒管吸收不全所致。由于宫腔镜子宫纵隔切除术在妊娠率和活产率方面取得了积极且令人满意的结果,以及诸多术后益处,它已取代了传统的剖腹手术方法。子宫纵隔切除术的目的是恢复子宫腔的正常解剖结构,这是成功着床及随后获得良好产科结局的前提条件。该治疗方法在复发性流产和原发性不明原因不孕症中均明确显示出其有效性。
宫腔镜子宫纵隔切除术操作简便、安全且能改善生殖结局,使治疗方法更为灵活。如今,宫腔镜子宫纵隔切除术是治疗纵隔子宫的常用方法,对不孕患者以及复发性流产或早产患者均有益,尤其是在考虑体外受精时。鉴于缺乏前瞻性、随机对照试验,特别讨论了何时治疗子宫纵隔的决策。