CpRu配合物催化的α-重氮-β-酮酯的原始反应活性。
Original reactivity of α-diazo-β- ketoesters catalyzed by CpRu complexes.
作者信息
Tortoreto Cecilia, Achard Thierry, Austeri Martina, Zeghida Walid, Lacour Jérôme
机构信息
University of Geneva Department of Chemistry Quai Ernest Ansermet 30 CH-1211 Geneva, Switzerland.
出版信息
Chimia (Aarau). 2014;68(4):243-7. doi: 10.2533/chimia.2014.243.
Using α-diazo-β-ketoesters as reagents and combinations of CpRu fragments and diimine ligands as catalysts, a series of original transformations have been obtained that can be rationalized by the formation of metal carbenes and metal-bound ylide intermediates. Interesting 1,3-dioxole, enol-acetal and 1,4-dioxene motifs are obtained directly when the reactive mixture is reacted in presence of aldehydes or ketones, THF and epoxides.
使用α-重氮-β-酮酯作为试剂，以CpRu片段和二亚胺配体的组合作为催化剂，已实现了一系列原始转化反应，这些反应可通过金属卡宾和金属结合的叶立德中间体的形成来进行合理解释。当反应混合物在醛或酮、四氢呋喃（THF）和环氧化物存在下进行反应时，可直接得到有趣的1,3-二氧戊环、烯醇缩醛和1,4-二烯结构单元。
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