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灼口综合征:最新进展

Burning Mouth Syndrome: update.

作者信息

Spanemberg Juliana Cassol, Rodríguez de Rivera Campillo Eugenia, Salas Enric Jané, López López José

机构信息

Bellvitge University Campus, Department of Odontoestomatology - School of Dentistry, Pabellón de Gobierno, C/Feixa LLarga s/n 08907 L'Hospitalet de Llobregat. Barcelona, Spain, Tel: +34-606457362; e-mail:

出版信息

Oral Health Dent Manag. 2014 Jun;13(2):418-24.

Abstract

Burning Mouth Syndrome (BMS) is a chronic disorder that predominately affects middle-aged women in the postmenopausal period. The condition is distinguished by burning symptoms of the oral mucosa and the absence of any clinical signs. The etiology of BMS is complex and it includes a variety of factors. Local, systemic and psychological factors such as stress, anxiety and depression are listed among the possible causes of BMS. BMS may sometimes be classified as BMS Type I, II or III. Although this syndrome is not accompanied by evident organic alterations and it does not present health risks, it can significantly reduce the patient's quality of life. This study analyzes the available literature related to BMS, and makes special reference to its therapeutic management. The pages that follow will also discuss the diagnostic criteria that should be respected, etiological factors, and clinical aspects. We used the PubMed database and searched it by using the keywords "burning mouth syndrome", "BMS and review", and "burning mouth and review", in the title or abstract of the publication. BMS treatment usually steers towards the management of the symptoms; however, the specific local factors that could play a significant role in worsening the oral burning sensation should be eradicated. The most widely accepted treatment options that show variable results include tricyclic antidepressants, benzodiazepines and antipsychotic drugs; nevertheless there are other therapies that can also be carried out. Professionals that work in the field of dentistry should formulate standardized symptomatic and diagnostic criteria in order to more easily identify the most effective and reliable strategies in BMS treatment through multidisciplinary research.

摘要

灼口综合征(BMS)是一种主要影响绝经后中年女性的慢性疾病。该病的特征是口腔黏膜有灼烧感且无任何临床体征。BMS的病因复杂,包括多种因素。局部、全身和心理因素,如压力、焦虑和抑郁,都被列为BMS可能的病因。BMS有时可分为I型、II型或III型。尽管这种综合征不伴有明显的器质性改变,也不存在健康风险,但它会显著降低患者的生活质量。本研究分析了与BMS相关的现有文献,并特别提及了其治疗管理。接下来的内容还将讨论应遵循的诊断标准、病因因素和临床方面。我们使用PubMed数据库,通过在出版物的标题或摘要中使用关键词“灼口综合征”、“BMS与综述”以及“灼口与综述”进行搜索。BMS的治疗通常侧重于症状管理;然而,应消除可能在加重口腔灼烧感方面起重要作用的特定局部因素。最广泛接受的治疗选择效果不一,包括三环类抗抑郁药、苯二氮䓬类药物和抗精神病药物;不过也可以采用其他疗法。牙科领域的专业人员应制定标准化的症状和诊断标准,以便通过多学科研究更轻松地确定BMS治疗中最有效和可靠的策略。

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